Liu Sisi, Wu Xiao, Zheng Yun, Zhang Afang, Dai Chengcai, Pan Linlin, Tu Qianqian, Dai Wen, Tang Wenhao, Zhang Hong
Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Medicine (Baltimore). 2025 Aug 8;104(32):e43864. doi: 10.1097/MD.0000000000043864.
Fat embolism syndrome (FES) is a complex syndrome with high in-hospital mortality and the diagnosis and treatment of FES remain challenging. In this article, we present a case report as well as a comprehensive review of trauma-related cases to enhance the understanding of FES.
An 18-year-old young man developed a fever, tachycardia, and dyspnea about 58 hours after the trauma. Chest computed tomography (CT) scan revealed blizzard-like changes on lung window obviously different from the initial chest CT.
The patient's medical history, clinical manifestations, and auxiliary examination results, especially the bronchoalveolar lavage fluid confirmed the diagnosis.
Chest CT scan demonstrated a significant absorption of the original lesions after the completion of methylprednisolone therapy for 3 days.
The patient was successfully discharged from the hospital without any complication.
When sudden dyspnea or altered consciousness arises, the possibility of FES should be taken into account. The bronchoalveolar lavage fluid can be helpful in diagnosing and assessing the severity of pulmonary embolism. Methylprednisolone can be employed in the treatment of FES while the complications should be considered.
脂肪栓塞综合征(FES)是一种复杂的综合征,院内死亡率高,其诊断和治疗仍然具有挑战性。在本文中,我们报告了一例病例,并对创伤相关病例进行了全面综述,以增进对FES的理解。
一名18岁青年男性在创伤后约58小时出现发热、心动过速和呼吸困难。胸部计算机断层扫描(CT)显示肺窗上有暴风雪样改变,与初始胸部CT明显不同。
患者的病史、临床表现和辅助检查结果,尤其是支气管肺泡灌洗术证实了诊断。
甲基强的松龙治疗3天后,胸部CT扫描显示原发病灶明显吸收。
患者成功出院,无任何并发症。
当突然出现呼吸困难或意识改变时,应考虑脂肪栓塞综合征的可能性。支气管肺泡灌洗术有助于诊断和评估肺栓塞的严重程度。甲基强的松龙可用于治疗脂肪栓塞综合征,但应考虑其并发症。