克罗恩病与溃疡性结肠炎发病机制的比较分析
Comparative analysis of the pathogenesis in Crohn's disease and ulcerative colitis.
作者信息
Agrawal Himanshu, Gupta Nikhil
机构信息
Department of Surgery, University College of Medical Sciences (University of Delhi), GTB Hospital, Delhi 110095, India.
Department of Surgery, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, Delhi 110001, India.
出版信息
World J Gastroenterol. 2025 Aug 7;31(29):109892. doi: 10.3748/wjg.v31.i29.109892.
Abstract
This article discusses Yang and Zhang's review on Crohn's disease and ulcerative colitis pathogenesis, emphasizing immune dysregulation, genetics, microbiota, and environmental factors. It highlights the need for personalized approaches, longitudinal studies, and better diagnostic tools to improve treatment strategies and patient outcomes in inflammatory bowel disease.
摘要
本文讨论了杨和张对克罗恩病和溃疡性结肠炎发病机制的综述，强调了免疫失调、遗传学、微生物群和环境因素。它强调了采用个性化方法、进行纵向研究以及使用更好的诊断工具以改善炎症性肠病的治疗策略和患者预后的必要性。
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本文引用的文献
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Navigating new horizons in inflammatory bowel disease: Integrative approaches and innovations.在炎症性肠病领域的新探索：综合方法与创新。
World J Gastroenterol. 2024 Nov 7;30(41):4411-4416. doi: 10.3748/wjg.v30.i41.4411.
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Cell. 2019 Aug 22;178(5):1041-1056. doi: 10.1016/j.cell.2019.07.045.
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The interplay between microbes and the immune response in inflammatory bowel disease.微生物与炎症性肠病中免疫应答的相互作用。
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A Personalized Approach to Managing Inflammatory Bowel Disease.一种管理炎症性肠病的个性化方法。
Gastroenterol Hepatol (N Y). 2016 May;12(5):308-15.
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Recent advances in IBD pathogenesis: genetics and immunobiology.炎症性肠病发病机制的最新进展：遗传学与免疫生物学
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