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微创经皮肾镜取石术联合输尿管鞘治疗肾结石的临床研究

A clinical study on minimally invasive percutaneous nephrolithotomy combined with ureteral access sheath for the treatment of kidney stones.

作者信息

Liu Boyang, Kang Yanjie, Shang Yafeng

机构信息

Department of Urology, Xinxiang Medical University, Xinxiang, China.

Department of Urology, Luoyang Central Hospital Affiliated to Zhengzhou University, Luoyang, China.

出版信息

Front Surg. 2025 Jul 29;12:1557603. doi: 10.3389/fsurg.2025.1557603. eCollection 2025.

DOI:10.3389/fsurg.2025.1557603
PMID:40799684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12339472/
Abstract

OBJECTIVE

To investigate the efficacy and safety of minimally invasive percutaneous nephrolithotomy (MPCNL) combined with ureteral access sheath in the treatment of complex kidney stones.

METHODS

Seventy patients with complex kidney stones in the author's hospital from June 2022 to December 2023 were randomized. There were 35 cases of minimally invasive percutaneous nephrolithotomy combined with ureteral access sheath and 35 cases of minimally invasive percutaneous nephrolithotomy alone.

RESULTS

Compared to the MPCNL group, the MPCNL + UAS group demonstrated a significantly shorter operative time (55.4 ± 9.2 min vs. 61.5 ± 12.8 min,  = 0.027), significantly lower intraoperative renal pelvic pressure (9.15 ± 4.13 mmHg vs. 11.35 ± 4.21 mmHg,  = 0.031), and a significantly lower incidence of postoperative Clavien complications ( < 0.05); however, there were no significant differences between the groups in postoperative creatinine change, stone clearance rate at 1 day postoperatively, or stone clearance rate at 30 days postoperatively ( > 0.05).

CONCLUSIONS

Minimally invasive percutaneous nephrolithotomy combined with ureteral access sheath is safe and effective in the treatment of complex kidney stones. Ureteral access sheath can significantly shorten the operation time of minimally invasive PCNL, keep the visual field clear, reduce the pressure of renal pelvis, and reduce the incidence of complications.

摘要

目的

探讨微创经皮肾镜取石术(MPCNL)联合输尿管鞘在治疗复杂性肾结石中的疗效和安全性。

方法

将2022年6月至2023年12月在作者所在医院的70例复杂性肾结石患者随机分组。其中35例采用微创经皮肾镜取石术联合输尿管鞘,35例仅采用微创经皮肾镜取石术。

结果

与MPCNL组相比,MPCNL + UAS组的手术时间明显缩短(55.4 ± 9.2分钟 vs. 61.5 ± 12.8分钟, = 0.027),术中肾盂压力明显降低(9.15 ± 4.13 mmHg vs. 11.35 ± 4.21 mmHg, = 0.031),术后Clavien并发症发生率明显降低( < 0.05);然而,两组在术后肌酐变化、术后1天结石清除率或术后30天结石清除率方面无显著差异( > 0.05)。

结论

微创经皮肾镜取石术联合输尿管鞘治疗复杂性肾结石安全有效。输尿管鞘可显著缩短微创PCNL的手术时间,保持视野清晰,降低肾盂压力,减少并发症的发生。

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本文引用的文献

1
Mini-PCNL - a boon for CKD patients with nephrolithiasis.微创经皮肾镜取石术——慢性肾脏病肾结石患者的福音。
Arab J Urol. 2023 Dec 26;22(2):115-120. doi: 10.1080/20905998.2023.2295041. eCollection 2024.
2
The influencing factors of infectious complications after percutaneous nephrolithotomy: a systematic review and meta-analysis.经皮肾镜碎石取石术后感染性并发症的影响因素:系统评价和荟萃分析。
Urolithiasis. 2022 Dec 14;51(1):17. doi: 10.1007/s00240-022-01376-5.
3
Does ureteral access sheath have an impact on ureteral injury?输尿管通路鞘会对输尿管损伤产生影响吗?
Urol Ann. 2022 Jan-Mar;14(1):1-7. doi: 10.4103/UA.UA_163_20. Epub 2022 Jan 20.
4
Mini Percutaneous Kidney Stone Removal: Applicable Technologies.经皮肾镜碎石取石术:适用技术。
Urol Clin North Am. 2022 Feb;49(1):161-173. doi: 10.1016/j.ucl.2021.08.003. Epub 2021 Oct 25.
5
Intrarenal Pressure: What Is Acceptable for Flexible Ureteroscopy and Percutaneous Nephrolithotomy?肾内压:软性输尿管镜碎石术和经皮肾镜取石术可接受的范围是多少?
Eur Urol Focus. 2021 Jan;7(1):31-33. doi: 10.1016/j.euf.2021.01.010. Epub 2021 Feb 3.
6
Characterization of intracalyceal pressure during ureteroscopy.肾盂内压在输尿管镜检查中的特点。
World J Urol. 2021 Mar;39(3):883-889. doi: 10.1007/s00345-020-03259-z. Epub 2020 May 27.
7
Risk factors for fever and sepsis after percutaneous nephrolithotomy.经皮肾镜取石术后发热和脓毒症的危险因素。
Asian J Urol. 2016 Apr;3(2):82-87. doi: 10.1016/j.ajur.2016.03.001. Epub 2016 Mar 11.
8
Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I.结石的外科治疗:美国泌尿外科学会/腔内泌尿外科学会指南,第一部分。
J Urol. 2016 Oct;196(4):1153-60. doi: 10.1016/j.juro.2016.05.090. Epub 2016 May 27.
9
Implementation of Ultramini Percutaneous Nephrolithotomy for Treatment of 2-3 cm Kidney Stones: A Preliminary Report.超微经皮肾镜取石术治疗2 - 3厘米肾结石的初步报告
J Endourol. 2015 Nov;29(11):1231-6. doi: 10.1089/end.2015.0171. Epub 2015 Aug 19.
10
Complications in percutaneous nephrolithotomy.经皮肾镜取石术的并发症
World J Urol. 2015 Aug;33(8):1069-77. doi: 10.1007/s00345-014-1400-8. Epub 2014 Sep 14.