• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

痉挛性脑瘫的下肢肌肉骨骼并发症

Lower Extremity Musculoskeletal Complications of Spastic Cerebral Palsy.

作者信息

Abdou Alexander, Spector Eli, Sidhu Sonam, Agrawal Devendra K

机构信息

Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California 91766, USA.

出版信息

J Orthop Sports Med. 2025;7(2):199-209. doi: 10.26502/josm.511500196. Epub 2025 Apr 21.

DOI:10.26502/josm.511500196
PMID:40800574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12341544/
Abstract

Spastic cerebral palsy (CP) frequently results in lower extremity musculoskeletal complications that cause disabling mobility loss and reduced quality of life. This review consolidates current understanding of these common complications, encompassing bony deformities (e.g., scoliosis, femoral anteversion, patella alta, ankle equinus), joint changes due to spasticity and contractures (e.g., hip subluxation, knee flexion contractures), spinal degeneration (e.g., cervical stenosis, lumbosacral spondylolisthesis), and neurologic dysfunction manifesting as pain and weakness. These pathologies are generally progressive, driven by impaired motor control, muscle spasticity, and shortened muscle-tendon units. By providing a comprehensive framework, this paper highlights the critical points facilitating a healthcare provider to recognize and understand these complications, ultimately improving patient care and outcomes.

摘要

痉挛型脑瘫(CP)常导致下肢肌肉骨骼并发症,造成致残性活动能力丧失和生活质量下降。本综述综合了目前对这些常见并发症的认识,包括骨骼畸形(如脊柱侧弯、股骨前倾、高位髌骨、马蹄足)、因痉挛和挛缩引起的关节变化(如髋关节半脱位、膝关节屈曲挛缩)、脊柱退变(如颈椎管狭窄、腰骶部椎体滑脱)以及表现为疼痛和无力的神经功能障碍。这些病理情况通常是渐进性的,由运动控制受损、肌肉痉挛和肌肉肌腱单位缩短所驱动。通过提供一个全面的框架,本文强调了有助于医疗保健提供者识别和理解这些并发症的关键点,最终改善患者护理和治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/dd692320c2e5/nihms-2077703-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/47843ebb54db/nihms-2077703-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/add2adabbe7e/nihms-2077703-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/ceb3b1a2edcd/nihms-2077703-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/5907518573d6/nihms-2077703-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/dd692320c2e5/nihms-2077703-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/47843ebb54db/nihms-2077703-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/add2adabbe7e/nihms-2077703-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/ceb3b1a2edcd/nihms-2077703-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/5907518573d6/nihms-2077703-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b024/12341544/dd692320c2e5/nihms-2077703-f0005.jpg

相似文献

1
Lower Extremity Musculoskeletal Complications of Spastic Cerebral Palsy.痉挛性脑瘫的下肢肌肉骨骼并发症
J Orthop Sports Med. 2025;7(2):199-209. doi: 10.26502/josm.511500196. Epub 2025 Apr 21.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
3
Intrathecal baclofen for treating spasticity in children with cerebral palsy.鞘内注射巴氯芬治疗小儿脑性瘫痪痉挛状态
Cochrane Database Syst Rev. 2015 Nov 13;2015(11):CD004552. doi: 10.1002/14651858.CD004552.pub2.
4
McKenzie Back Exercises麦肯齐背部练习
5
Assessing Gross Motor and Gait Function Using Hip-Knee Cyclograms in Ambulatory Children with Spastic Cerebral Palsy.使用髋膝运动图评估痉挛型脑性瘫痪门诊儿童的粗大运动和步态功能
Sensors (Basel). 2025 Jul 18;25(14):4485. doi: 10.3390/s25144485.
6
Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy.A型肉毒毒素作为辅助治疗手段用于痉挛型脑瘫患儿上肢的治疗。
Cochrane Database Syst Rev. 2004(3):CD003469. doi: 10.1002/14651858.CD003469.pub2.
7
Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy.A型肉毒毒素作为治疗痉挛型脑瘫患儿上肢的辅助治疗手段。
Cochrane Database Syst Rev. 2004 Oct 18(4):CD003469. doi: 10.1002/14651858.CD003469.pub3.
8
Spinal Muscular Atrophy脊髓性肌萎缩症
9
AP-4-Associated Hereditary Spastic ParaplegiaAP-4相关遗传性痉挛性截瘫
10
Trihexyphenidyl for dystonia in cerebral palsy.用于治疗脑瘫肌张力障碍的苯海索
Cochrane Database Syst Rev. 2018 May 15;5(5):CD012430. doi: 10.1002/14651858.CD012430.pub2.

本文引用的文献

1
The effect of foot deformities on the interplay of forces within the foot: An analysis of multi-segment foot joint moments in cerebral palsy.足部畸形对足部内作用力相互作用的影响:脑瘫患者多节段足部关节力矩分析
Gait Posture. 2025 Mar;117:115-120. doi: 10.1016/j.gaitpost.2024.12.006. Epub 2024 Dec 9.
2
Prevalence of valgus and varus foot deformities in 2784 children with cerebral palsy, a register-based cross-sectional study.2784 例脑瘫儿童的足内翻和足外翻畸形患病率:基于登记的横断面研究。
BMC Musculoskelet Disord. 2024 Nov 19;25(1):930. doi: 10.1186/s12891-024-08029-1.
3
Neuromuscular impairments of cerebral palsy: contributions to gait abnormalities and implications for treatment.
脑瘫的神经肌肉损伤:对步态异常的影响及治疗意义
Front Hum Neurosci. 2024 Sep 18;18:1445793. doi: 10.3389/fnhum.2024.1445793. eCollection 2024.
4
Cerebral palsy in children: A clinical practice review.儿童脑瘫:临床实践综述。
Curr Probl Pediatr Adolesc Health Care. 2024 Nov;54(11):101673. doi: 10.1016/j.cppeds.2024.101673. Epub 2024 Aug 20.
5
Knee and ankle range of motion and spasticity from childhood into adulthood: a longitudinal cohort study of 3,223 individuals with cerebral palsy.膝关节和踝关节活动范围及痉挛:3223 例脑瘫患者从儿童到成年的纵向队列研究。
Acta Orthop. 2024 May 6;95:200-205. doi: 10.2340/17453674.2024.40606.
6
Relationship Between Postural Asymmetry, Balance, and Pain in Children With Spastic Cerebral Palsy.痉挛型脑瘫儿童姿势不对称、平衡与疼痛的关系。
Pediatr Neurol. 2024 Jun;155:84-90. doi: 10.1016/j.pediatrneurol.2024.03.018. Epub 2024 Mar 24.
7
The relationship between hip displacement, scoliosis, and pelvic obliquity in 106 nonambulatory children with cerebral palsy: a longitudinal retrospective population-based study.106 例非卧床脑瘫儿童髋关节位移、脊柱侧凸和骨盆倾斜的关系:一项基于人群的纵向回顾性研究。
Acta Orthop. 2024 Jan 30;95:55-60. doi: 10.2340/17453674.2024.39915.
8
Maternal body mass index and cerebral palsy in children: A systematic review and dose-response meta-analysis.母亲体重指数与儿童脑瘫:系统评价和剂量反应荟萃分析。
Paediatr Perinat Epidemiol. 2024 May;38(4):345-356. doi: 10.1111/ppe.13033. Epub 2023 Dec 26.
9
The Experience of Living through the Transition from Adolescence to Adulthood for Young People with Cerebral Palsy.脑瘫青年从青春期过渡到成年期的生活经历。
Occup Ther Health Care. 2025 Jan;39(1):72-91. doi: 10.1080/07380577.2023.2211669. Epub 2023 May 15.
10
In utero Exposure to Maternal Diabetes and the Risk of Cerebral Palsy: A Population-based Cohort Study.子宫内暴露于母体糖尿病与脑瘫风险:基于人群的队列研究。
Epidemiology. 2023 Mar 1;34(2):247-258. doi: 10.1097/EDE.0000000000001574. Epub 2022 Dec 1.