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一名克罗恩病患者的独特胆石性肠梗阻病例：结石嵌顿于回肠腺癌中。

A Unique Case of Gallstone Ileus in a Patient With Crohn's Disease: Stone Impaction in an Ileal Adenocarcinoma.

作者信息

Antenucci Tommaso, Arena Rosario

机构信息

Department of Medicine and Surgery University of Bologna Bologna Italy.

University Hospital Arcispedale Sant'anna of Ferrara Cona Italy.

出版信息

Clin Case Rep. 2025 Aug 11;13(8):e70793. doi: 10.1002/ccr3.70793. eCollection 2025 Aug.

DOI:10.1002/ccr3.70793
PMID:40800587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12339411/
Abstract

Gallstone ileus represents an uncommon etiology of mechanical intestinal obstruction. Individuals with Crohn's disease are predisposed to both increased gallstone formation and a heightened risk of gastrointestinal malignancy. This case highlights the necessity of excluding malignancy when evaluating newly developed strictures in this patient population.

摘要

胆结石性肠梗阻是机械性肠梗阻的一种罕见病因。克罗恩病患者既易患胆结石，患胃肠道恶性肿瘤的风险也更高。该病例强调了在评估这一患者群体新出现的狭窄时排除恶性肿瘤的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/ae6c2c6a9c64/CCR3-13-e70793-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/92be51f0e21b/CCR3-13-e70793-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/ffee9c0333c5/CCR3-13-e70793-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/62798e92c484/CCR3-13-e70793-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/9cdbcb5c6a91/CCR3-13-e70793-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/ae6c2c6a9c64/CCR3-13-e70793-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/92be51f0e21b/CCR3-13-e70793-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/ffee9c0333c5/CCR3-13-e70793-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/62798e92c484/CCR3-13-e70793-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/9cdbcb5c6a91/CCR3-13-e70793-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e94/12339411/ae6c2c6a9c64/CCR3-13-e70793-g001.jpg

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本文引用的文献

1
Risk Factors for Gallstones in Crohn's Disease: A Systematic Review and Meta-Analysis.克罗恩病患者发生胆结石的风险因素：系统评价和荟萃分析。
Dig Dis Sci. 2024 Nov;69(11):4187-4202. doi: 10.1007/s10620-024-08597-1. Epub 2024 Sep 25.
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Small Bowel Cancer in Crohn's Disease.克罗恩病中的小肠癌
Cancers (Basel). 2024 Aug 21;16(16):2901. doi: 10.3390/cancers16162901.
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Cancer in Inflammatory Bowel Disease.炎症性肠病相关癌症。
Gastroenterol Clin North Am. 2022 Sep;51(3):649-666. doi: 10.1016/j.gtc.2022.05.003. Epub 2022 Aug 30.
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Gallstone ileus: a review.胆石性肠梗阻：综述
BMJ Open Gastroenterol. 2019 Nov 24;6(1):e000344. doi: 10.1136/bmjgast-2019-000344. eCollection 2019.
5
Is gallstone disease associated with inflammatory bowel diseases? A meta-analysis.胆结石疾病与炎症性肠病有关联吗？一项荟萃分析。
J Dig Dis. 2015 Nov;16(11):634-41. doi: 10.1111/1751-2980.12286.
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Gallstone ileus in a patient with Crohn's disease: a case report.克罗恩病患者的胆石性肠梗阻：一例报告
Acta Chir Belg. 2012 Sep-Oct;112(5):390-2. doi: 10.1080/00015458.2012.11680859.
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Gallstone ileus an unusual reason for right iliac fossa pain in Crohn's disease: a case report.胆结石性肠梗阻——克罗恩病患者右下腹疼痛的罕见原因：一例报告
Cases J. 2009 Sep 16;2:9285. doi: 10.1186/1757-1626-0002-0000009285.
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The risk of cancer in patients with Crohn's disease.克罗恩病患者患癌风险
Dis Colon Rectum. 2007 Jun;50(6):839-55. doi: 10.1007/s10350-006-0848-z.
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Gallstone ileus in patient with Crohn's disease: report of a clinical observation.克罗恩病患者的胆石性肠梗阻：临床观察报告
Surg Endosc. 2006 Apr;20(4):703-4. doi: 10.1007/s00464-005-0579-6.
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Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark.克罗恩病患者的肠道及肠外癌症：丹麦哥本哈根郡一项基于人群队列的随访研究
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