Murthy Aravind Baskar, Sagar Kallepu Rishika, Ramchandraiah Varshini Neelathalli, Narasimhan Murali
Department of Dermatology, Venereology and Leprosy, SRM Medical College Hospital and Research Centre, Kattankulathur Campus, Chengalpattu, Tamil Nadu, India.
Indian Dermatol Online J. 2025 Sep 1;16(5):778-781. doi: 10.4103/idoj.idoj_1087_24. Epub 2025 Aug 13.
Benign lichenoid keratosis (BLK), also known as lichen planus-like keratosis, is a benign cutaneous lesion of unknown etiology with overlapping clinical and dermoscopic features with malignant lesions. A 52-year-old female presented with a 10- years history of a single asymptomatic lesion on the left gluteal region not associated with loss of weight, loss of appetite, or other systemic symptoms. Clinical examination revealed a single well-defined violaceous to hyperpigmented plaque of approximately 4 cm × 3 cm in size, on the lateral aspect of the left gluteal region. Dermoscopic examination showed overlapping features of BLK and melanoma. Ultraviolet (UV)dermoscopy showed 'dermoscopic UV blink sign' and areas of blue, yellowish-green, and red fluorescence. Histopathological examination showed features suggestive of BLK with no cellular atypia. The patient was started on 5% imiquimod cream 5 days a week and advised to follow up. This case emphasizes the importance of clinical, dermoscopic, UV reflectance dermoscopic, and histopathological correlation in establishing the diagnosis of BLK masquerading as melanoma with regression, thus aiding in the avoidance of unnecessary surgeries.
良性苔藓样角化病(BLK),也称为扁平苔藓样角化病,是一种病因不明的良性皮肤病变,其临床和皮肤镜特征与恶性病变有重叠。一名52岁女性,左侧臀部长有单个无症状病变10年,与体重减轻、食欲不振或其他全身症状无关。临床检查发现左侧臀外侧有一个边界清晰的紫罗兰色至色素沉着过度的斑块,大小约为4厘米×3厘米。皮肤镜检查显示BLK和黑色素瘤有重叠特征。紫外线(UV)皮肤镜检查显示“皮肤镜UV闪烁征”以及蓝色、黄绿色和红色荧光区域。组织病理学检查显示有提示BLK的特征,无细胞异型性。患者开始每周5天外用5%咪喹莫特乳膏,并建议随访。该病例强调了临床、皮肤镜、UV反射皮肤镜和组织病理学相关性在诊断伪装成消退期黑色素瘤的BLK中的重要性,从而有助于避免不必要的手术。