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[冰岛的颈动脉瘤夹层:流行病学、治疗与预后]

[Cervical artery dissection in Iceland: epidemiology, treatment and prognosis].

作者信息

Andradottir Idunn, Thors Brynhildur, Sveinsson Olafur

机构信息

University of Iceland, Faculty of Medicin.

Department of Neurology, University Hospital of Iceland, Reykjavik, Iceland.

出版信息

Laeknabladid. 2024 Nov;110(11):506-511. doi: 10.17992/lbl.2024.11.812.

Abstract

BACKGROUND

Cervical artery dissection is a common cause of ischemic stroke in young adults and middle-aged individuals. Due to advances in imaging techniques and increased knowledge, dissections are now diagnosed much more frequently than before. This study aimed to investigate the incidence of cervical artery dissection in Iceland from 2005 to 2023.

METHODS

A retrospective study was conducted using medical records of individuals diagnosed with cervical artery dissection in Iceland between January 1, 2005, and December 31, 2023. The factors examined included gender, year of diagnosis, age at diagnosis, symptoms, risk factors, treatment, and prognosis. Data processing was performed using Excel® and Rstudio.

RESULTS

The study sample consisted of 107 individuals, including 37 women and 70 men. The average incidence was 1.62 per 100,000 people per year. The incidence increased over the period, being 2.7 times higher in the latter half compared to the former. The average age of diagnosis was 50 years (range 18-101 years). The most common symptom was pain (72%), followed by sensory disturbances (67%), motor disturbances (49%), and Horner's syndrome (36%). Half of the patients experienced an ischemic stroke (51%). Five individuals (4.6%) had a recurrent dissection during the follow-up period. Dissections occurred in the internal carotid artery in 56% of cases and the vertebral artery in 44% of cases. All patients received antiplatelet and/or anticoagulant therapy. After 3-6 months, 77% had no or mild disability (0-2 on the modified Rankin scale).

DISCUSSION

The incidence of cervical artery dissection in Iceland is consistent with findings from other studies. Diagnoses have increased in recent years, and the average incidence has risen. The majority of patients achieved good recovery, indicating effective diagnosis and treatment of cervical artery dissection in Iceland.

摘要

背景

颈动脉硬化夹层是年轻成年人和中年个体缺血性中风的常见病因。由于成像技术的进步和认识的增加,现在夹层的诊断比以前更加频繁。本研究旨在调查2005年至2023年冰岛颈动脉硬化夹层的发病率。

方法

采用回顾性研究,使用2005年1月1日至2023年12月31日期间冰岛诊断为颈动脉硬化夹层的个体的医疗记录。检查的因素包括性别、诊断年份、诊断时年龄、症状、危险因素、治疗和预后。数据处理使用Excel®和Rstudio进行。

结果

研究样本包括107名个体,其中37名女性和70名男性。平均发病率为每年每10万人1.62例。在此期间发病率有所增加,后半期比前半期高2.7倍。诊断的平均年龄为50岁(范围18 - 101岁)。最常见的症状是疼痛(72%),其次是感觉障碍(67%)、运动障碍(49%)和霍纳综合征(36%)。一半的患者发生了缺血性中风(51%)。5名个体(4.6%)在随访期间出现复发性夹层。56%的病例发生在颈内动脉,44%的病例发生在椎动脉。所有患者均接受抗血小板和/或抗凝治疗。3 - 6个月后,77%的患者无残疾或轻度残疾(改良Rankin量表评分为0 - 2分)。

讨论

冰岛颈动脉硬化夹层的发病率与其他研究结果一致。近年来诊断有所增加,平均发病率上升。大多数患者恢复良好,表明冰岛对颈动脉硬化夹层的诊断和治疗有效。

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