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人道主义环境下骨科内固定手术的临床结果:也门亚丁无国界医生组织(MSF)创伤中心的一项回顾性队列研究

Clinical outcomes of internal fixation orthopaedic surgery in humanitarian settings: a retrospective cohort study at the Médecins Sans Frontières (MSF) trauma centre in Aden, Yemen.

作者信息

Malaeb Rami, Hussain Taha, Ayyash Fares, Abdullah Abdulsalam, Ahmed Hameed S, Abdulrahman Khaled, Al Haj Adel, Bin Shahna Hesham, Zelikova Evgenia, Hassanin Ibrahim, Poulet Elisabeth, Herard Patrick, Fakhri Rasheed

机构信息

Epicentre, Paris, France.

Médecins Sans Frontières, Paris, France.

出版信息

Int Orthop. 2025 Aug 13. doi: 10.1007/s00264-025-06616-y.

Abstract

PURPOSE

The Aden Trauma Centre in Yemen, supported by Médecins Sans Frontières (MSF), introduced internal fixation (IF) procedures to address the high burden of fractures as a result of road traffic accidents and conflict-related injuries. This study aimed to describe the clinical characteristics of patients undergoing IF, evaluate their complication and healing outcomes, and explore factors influencing postoperative results.

METHODS

A retrospective cohort design was employed, including all patients who underwent internal fixation-using SIGN nails or plates/screws-between January and December 2022. Demographic information, fracture characteristics, surgical techniques, and postoperative outcomes were analyzed. Cox proportional hazards models were used to identify key predictors of complications and bone healing.

RESULTS

A total of 177 patients (208 fractures) were included. The overall complication rate was 14.4%. Open fractures and comorbidities were significant predictors of complications, while type of implant (SIGN nail vs. plate/screws) did not affect complication risk. Around three-quarters of fractures achieved radiographic healing at a median of five to six months. Infection and other complications emerged as major risk factors for delayed or impaired union. About a quarter of patients defaulted from care, potentially underestimating late complications and nonunion rates.

CONCLUSION

Findings indicate that IF is feasible and effective in this high-need, low-resource context, demonstrating complication rates in line with global estimates. Open fractures, comorbidities, and limited follow-up infrastructure remain the main challenges to optimizing outcomes in such contexts.

摘要

目的

在无国界医生组织的支持下,也门的亚丁创伤中心引入了内固定(IF)手术,以应对因道路交通事故和冲突相关伤害导致的高骨折负担。本研究旨在描述接受内固定治疗患者的临床特征,评估其并发症和愈合结果,并探讨影响术后结果的因素。

方法

采用回顾性队列设计,纳入2022年1月至12月期间所有使用SIGN髓内钉或钢板/螺钉进行内固定的患者。分析人口统计学信息、骨折特征、手术技术和术后结果。使用Cox比例风险模型确定并发症和骨愈合的关键预测因素。

结果

共纳入177例患者(208处骨折)。总体并发症发生率为14.4%。开放性骨折和合并症是并发症的重要预测因素,而植入物类型(SIGN髓内钉与钢板/螺钉)不影响并发症风险。约四分之三的骨折在五到六个月的中位时间实现了影像学愈合。感染和其他并发症是延迟愈合或愈合受损的主要危险因素。约四分之一的患者未接受后续治疗,这可能低估了晚期并发症和骨不连发生率。

结论

研究结果表明,在这种高需求、资源匮乏的情况下,内固定是可行且有效的,并发症发生率与全球估计相符。开放性骨折、合并症和有限的随访基础设施仍然是在这种情况下优化治疗结果的主要挑战。

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