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Leveraging hepatitis B vaccination to consolidate functional cure: reigniting the humoral axis in chronic HBV infection.

作者信息

Ren Shan, Zheng Sujun, Chen Xinyue

机构信息

First Department of Liver Disease Center, Beijing Youan Hospital, Capital Medical University, Beijing, People's Republic of China.

出版信息

Emerg Microbes Infect. 2025 Dec;14(1):2547723. doi: 10.1080/22221751.2025.2547723. Epub 2025 Aug 26.

DOI:10.1080/22221751.2025.2547723
PMID:40802993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12381986/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3526/12381986/5256d4fdd11e/TEMI_A_2547723_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3526/12381986/ade455a2a26a/TEMI_A_2547723_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3526/12381986/5256d4fdd11e/TEMI_A_2547723_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3526/12381986/ade455a2a26a/TEMI_A_2547723_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3526/12381986/5256d4fdd11e/TEMI_A_2547723_F0002_OC.jpg

相似文献

[1]
Leveraging hepatitis B vaccination to consolidate functional cure: reigniting the humoral axis in chronic HBV infection.

Emerg Microbes Infect. 2025-12

[2]
Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels.

J Hepatol. 2024-5

[3]
The HBV seroprevalence and immune responses to hepatitis B vaccination among college students from four universities in China.

Vaccine. 2025-8-13

[4]
Recurrence risk factors for chronic hepatitis B virus-infected patients who achieve functional cure with pegylated interferon-α-2b-based therapy: a multicenter pilot study.

Virol J. 2025-5-19

[5]
Enhanced hepatitis B virus-specific immunity by combining neutralizing antibody therapy and DNA vaccination in a murine model of chronic hepatitis B virus infection.

Hepatology. 2025-8-1

[6]
Varied immune responses of HBV-specific B cells in patients undergoing pegylated interferon-alpha treatment for chronic hepatitis B.

J Hepatol. 2024-12

[7]
Vaccines for preventing hepatitis B in health-care workers.

Cochrane Database Syst Rev. 2005-10-19

[8]
Clinical study of hepatitis B vaccine in achieving hepatitis B surface antibody seroconversion in patients with functional cure.

Braz J Infect Dis. 2023

[9]
Peg-IFNα combined with hepatitis B vaccination contributes to HBsAg seroconversion and improved immune function.

Virol J. 2024-3-30

[10]
Evaluation of anti-HBs seropositivity rates in children with familial mediterranean fever.

Eur J Pediatr. 2025-5-29

本文引用的文献

[1]
A greater frequency of circulating CCR7loPD-1hi follicular helper T cells indicates a durable clinical cure after Peg IFN-α therapy in chronic hepatitis B patients.

Hepatol Commun. 2025-4-14

[2]
The core cellular network modulates immune phenotype switching in hepatitis B.

Sci Bull (Beijing). 2025-9-15

[3]
The Impact of Hepatitis B Surface Antigen Reduction via Small Interfering RNA Treatment on Natural and Vaccine (BRII-179)-Induced Hepatitis B Virus-Specific Humoral and Cellular Immune Responses.

Gastroenterology. 2025-3-3

[4]
The impact of hepatitis B surface antigen seroconversion on the durability of functional cure induced by pegylated interferon alpha treatment.

Virol J. 2024-10-3

[5]
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection.

Nature. 2024-7

[6]
Peg-IFNα combined with hepatitis B vaccination contributes to HBsAg seroconversion and improved immune function.

Virol J. 2024-3-30

[7]
Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity.

J Hepatol. 2024-7

[8]
Therapeutic vaccine-induced plasma cell differentiation is defective in the presence of persistently high HBsAg levels.

J Hepatol. 2024-5

[9]
Clinical study of hepatitis B vaccine in achieving hepatitis B surface antibody seroconversion in patients with functional cure.

Braz J Infect Dis. 2023

[10]
The potential effect of HBV vaccination on off-treatment HBsAg reversion after interferon-induced HBsAg clearance.

Hum Vaccin Immunother. 2023-12-31

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