Suppr超能文献

递归自我反馈能够使患有病理性语言混合的失语症患者进行目标语言生成。

Recursive self-feedback enables target language production in aphasia with pathological language mixing.

作者信息

Imaezue Gerald C, Davis Celine, Maram Krishna Veni, Ajayi David, Goral Mira

机构信息

Department of Communication Sciences and Disorders, University of South Florida, Tampa, FL, USA.

Department of Communication Sciences and Disorders, University of South Florida, Tampa, FL, USA.

出版信息

Brain Lang. 2025 Aug 12;270:105633. doi: 10.1016/j.bandl.2025.105633.

Abstract

Stroke in bilingual adults can lead to aphasia with pathological language mixing (PLM), a rare neurological condition with limited treatment options. Recursive self-feedback (RSF) offers a self-directed approach, allowing individuals with PLM to iteratively self-monitor and correct their language mixing independently. We demonstrated the effects of RSF in a 59-year-old female bilingual speaker of Spanish and English (Patient P3) with severe Broca's aphasia and PLM, 67-months poststroke. Over 14 intensive RSF sessions (2 h/day, 5 days/week, for 3 weeks), P3 used a mobile app to self-correct her mixing errors and increase the proportion of English words in her spontaneous speech. Post-treatment assessments showed improvements across both treated and untreated narrative prompts, with an 11-point increase in her Aphasia Quotient on the English version of the Western Aphasia Battery-Revised. These findings demonstrate that RSF enables target language production, yielding clinically meaningful language recovery in P3 without external cueing, modelling or feedback. RSF is a promising procedure for aphasia therapy, opening new pathways for targeting language access, control and recovery in aphasia and PLM.

摘要

双语成年人中风可导致伴有病理性语言混合(PLM)的失语症,这是一种罕见的神经系统疾病,治疗选择有限。递归自我反馈(RSF)提供了一种自我指导的方法,使患有PLM的个体能够迭代地自我监测并独立纠正其语言混合。我们展示了RSF对一名59岁说西班牙语和英语的双语女性(患者P3)的效果,该患者患有严重的布罗卡失语症和PLM,中风后67个月。在14次强化RSF治疗(每天2小时,每周5天,共3周)中,P3使用移动应用程序自我纠正其混合错误,并增加其自发言语中英语单词的比例。治疗后评估显示,在经过治疗和未经过治疗的叙述提示中均有改善,在修订版西方失语症量表英文版上,她的失语商增加了11分。这些发现表明,RSF能够实现目标语言的生成,在没有外部提示、示范或反馈的情况下,使P3实现具有临床意义的语言恢复。RSF是一种很有前景的失语症治疗方法,为针对失语症和PLM中的语言获取、控制和恢复开辟了新途径。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验