Borchers-Arriagada Nicolas, Chaston Timothy B, Morgan Geoffrey G, Knibbs Luke D, Johnston Fay H
Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia; Centre for Safe Air, NHMRC Centre for Research Excellence, Hobart, Tasmania, Australia.
HEAL Global Research Centre, Health Research Institute, University of Canberra, Canberra, Australian Capital Territory, Australia; Centre for Safe Air, NHMRC Centre for Research Excellence, Hobart, Tasmania, Australia; Healthy Environments and Lives (HEAL), National Research Network, Australia.
Environ Res. 2025 Aug 11;285(Pt 4):122519. doi: 10.1016/j.envres.2025.122519.
Fine particulate matter (PM) and nitrogen dioxide (NO) are associated with multiple health risks, including death. In Australia, the mortality burden attributable to PM has been estimated, but there are no published estimates for NO or the combined impacts of both pollutants.
To estimate the mortality burden attributable to PM and NO from all anthropogenic sources and traffic-related air pollution (TRAP) in Australia.
We used previously published predictions for all source PM and NO and chemical transport model outputs to estimate TRAP-related concentrations. We estimated the attributable number of deaths by applying a life tables approach. We used publicly available population and mortality data together with effect estimates obtained from global meta-analyses, and incorporated recent recommendations for including single- and two-pollutant effect estimates into health impact assessment methods for air pollution. We did a series of sensitivity analyses to assess the influence of different modelling approaches and choices on our results.
In 2015, an estimated 3684 (95 % CI, 3051-4350) premature deaths were attributable to air pollution from all sources, with 51 % (95 % CI, 19 %-86 %) linked to TRAP. Using mutually adjusted coefficients from two pollutant models and summing results did not appreciably change estimates derived from a single pollutant marker. Our results support PM as a reliable marker for mortality impacts from diverse emission sources, and NO as a robust marker for TRAP-related mortality in Australia. Sensitivity analyses including exposures below low-threshold cutoffs, using estimates for low pollution settings, and using location-specific threshold cutoffs for NO, yielded higher mortality estimates. This suggests our results may be conservative.
Air pollution remains a significant contributor to mortality in Australia. Reducing exposure, particularly from TRAP, could yield substantial public health benefits. Policies promoting cleaner transport modes offer a promising avenue for rapid improvement.
细颗粒物(PM)和二氧化氮(NO)与多种健康风险相关,包括死亡风险。在澳大利亚,已对归因于PM的死亡负担进行了估算,但尚无关于NO或两种污染物综合影响的公开估算。
估算澳大利亚所有人为源以及与交通相关的空气污染(TRAP)中的PM和NO所致的死亡负担。
我们使用先前发表的所有源PM和NO的预测以及化学传输模型输出,以估算与TRAP相关的浓度。我们采用生命表方法估算了可归因死亡数。我们使用公开可得的人口和死亡率数据以及从全球荟萃分析中获得的效应估计值,并纳入了将单污染物和双污染物效应估计值纳入空气污染健康影响评估方法的最新建议。我们进行了一系列敏感性分析,以评估不同建模方法和选择对我们结果的影响。
2015年,估计有3684例(95%可信区间,3051 - 4350)过早死亡可归因于所有来源的空气污染,其中51%(95%可信区间,19% - 86%)与TRAP有关。使用来自双污染物模型的相互调整系数并汇总结果,并未显著改变从单一污染物标志物得出的估计值。我们的结果支持将PM作为来自不同排放源的死亡率影响的可靠标志物,以及将NO作为澳大利亚与TRAP相关死亡率的有力标志物。敏感性分析包括低于低阈值临界值的暴露、使用低污染环境的估计值以及使用特定地点的NO阈值临界值,得出了更高的死亡率估计值。这表明我们的结果可能较为保守。
空气污染仍是澳大利亚死亡率的一个重要因素。减少暴露,尤其是减少TRAP暴露,可带来显著的公共卫生效益。推广更清洁交通方式的政策为快速改善提供了一条有前景的途径。