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宫腔镜直视下LNG-IUS尾丝固定于浅表肌层的临床疗效分析

Clinical efficacy analysis of LNG-IUS tail anchoring to the superficial myometrium under hysteroscopic direct vision.

作者信息

Li Qiaofen, Huang Zongyan, Xiang Huimin, Chen Peilin, Wu Shiying, Hu Weiwei, Xiao Songshu

机构信息

Department of Obstetrics and Gynecology, Third Xiangya Hospital, Central South University, No. 138 Tongzipo Road, Yuelu District, Changsha, Hunan, China.

出版信息

BMC Surg. 2025 Aug 13;25(1):370. doi: 10.1186/s12893-025-02982-x.

Abstract

OBJECTIVE

To investigate the clinical efficacy of levonorgestrel-releasing intrauterine system (LNG-IUS) tail anchoring to the superficial myometrium under hysteroscopic direct vision.

METHODS

From March 1, 2017, to March 1, 2022, 206 patients at the Third Xiangya Hospital of Central South University who had a history of at least one LNG-IUS expulsion and who required replacement of the LNG-IUS were retrospectively analyzed. Patients were divided into a common placement group and an anchoring group according to the placement method used for the LNG-IUS. Between-group comparisons of the re-expulsion rate and adverse reactions were performed, and the clinical efficacy of anchoring was evaluated. The patients in the anchoring group were divided into short-tail and long-tail groups on the basis of the length of the tail.

RESULTS

After propensity score matching (PSM), the re-expulsion rate was 18.87% for the anchoring group and 43.40% for the common placement group. There was a significant difference in re-expulsion rates between the two groups (P< 0.05), with the anchoring group having a significantly lower rate than the common placement group. Additionally, the re-expulsion rate of the long-tail group (6.90%) was significantly lower than that of the short-tail group (28.77%) (P< 0.05). The use of anchoring surgery did not lead to a higher incidence of uterine perforation or infection.

CONCLUSIONS

For patients with a history of levonorgestrel-releasing intrauterine system expulsion, anchoring the LNG-IUS tail in the superficial uterine myometrium under hysteroscopy can effectively prevent re-expulsion and significantly reduce the re-expulsion rate, especially when the long tail anchoring method is used. This technique is efficacious and warrants widespread adoption.

摘要

目的

探讨宫腔镜直视下左炔诺孕酮宫内节育系统(LNG-IUS)尾丝固定于子宫浅肌层的临床疗效。

方法

回顾性分析2017年3月1日至2022年3月1日在中南大学湘雅三医院有至少1次LNG-IUS排出史且需要更换LNG-IUS的206例患者。根据LNG-IUS的放置方法将患者分为普通放置组和固定组。比较两组的再排出率和不良反应,并评估固定的临床疗效。固定组患者根据尾丝长度分为短尾组和长尾组。

结果

倾向得分匹配(PSM)后,固定组的再排出率为18.87%,普通放置组为43.40%。两组再排出率差异有统计学意义(P<0.05),固定组显著低于普通放置组。此外,长尾组的再排出率(6.90%)显著低于短尾组(28.77%)(P<0.05)执行。使用固定手术不会导致子宫穿孔或感染的发生率更高。

结论

对于有左炔诺孕酮宫内节育系统排出史的患者,宫腔镜下将LNG-IUS尾丝固定于子宫浅肌层可有效预防再排出,显著降低再排出率,尤其是采用长尾固定法时。该技术有效,值得广泛应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea8/12351962/072879e16a7a/12893_2025_2982_Fig1_HTML.jpg

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