François P, Guyot A, Jean D, Joannard A, Micoud M, Beaudoing A
Pediatrie. 1985 Mar;40(2):99-106.
The complications of varicella have been studied in 103 cases of hospitalized children. The patients have been divided into two groups: group I comprises 94 previously healthy children; group II is made up of 9 children who have been treated by corticotherapy for a long time. The frequency of the complications is not statistically different between the two groups. On the other hand, all the fatal complications are observed in group II (3 deaths out of 9 patients). This investigation is in accordance with published data which allows us to characterize a high risk population for life threatening varicella: patients with congenital or acquired cell immunity deficiency. This group requires special therapy: vaccination, specific immunoglobulins and acyclovir.
对103例住院儿童水痘并发症进行了研究。患者被分为两组:第一组包括94名先前健康的儿童;第二组由9名长期接受皮质激素治疗的儿童组成。两组并发症的发生率在统计学上无差异。另一方面,所有致命并发症均出现在第二组(9例患者中有3例死亡)。本研究与已发表的数据一致,这些数据使我们能够确定水痘危及生命的高危人群:先天性或后天性细胞免疫缺陷患者。这组患者需要特殊治疗:接种疫苗、使用特异性免疫球蛋白和阿昔洛韦。