Characterisation of the Ovine Gene in Chinese Tan Lambs and Its Impact on Selected Wool Traits.

Wool has distinctive biological, physical, and chemical properties that contribute to its value both for the sheep and in global fibre and textile markets. Its fibres are primarily composed of proteins, principally keratin and keratin-associated proteins (KAPs). To better comprehend the genes that underpin key wool traits, this study examined the keratin-associated protein 36-1 gene () in Chinese Tan lambs. We identified three previously reported alleles of the gene (named , and ) that were present in the lambs studied, with genotype frequencies as follows: 2.0% ( = 5; ), 6.9% ( = 17; ), 13.8% ( = 34; ), 8.9% ( = 22; ), 33.4% ( = 82; ) and 35.0% ( = 86; ). The frequencies of the individual alleles in the Chinese Tan lambs were 12.4%, 29.1% and 58.5% for alleles , and , respectively. The three alleles were in Hardy-Weinberg Equilibrium. In an association analysis, it was revealed that allele was associated with variation in the mean fibre curvature of the fine wool of the Chinese Tan lambs, but this association was not observed in their heterotypic hair fibres. This finding suggests that might be differentially expressed in the wool follicles that produce the two fibre types, and that along with other genes, it may be involved in determining fibre curvature and the distinctive curly coat of the lambs.