Tinkilic Seymanur, Turker Perim Fatma, Yilmaz Can Selim, Akdogan Kayhan Meral, Ari Derya, Turan Gökce Dilara
Department of Nutrition and Dietetic, Baskent University, Ankara 06790, Türkiye.
Department of Nutrition and Dietetics, Acibadem Mehmet Ali Aydinlar University, Istanbul 34752, Türkiye.
Healthcare (Basel). 2025 Aug 5;13(15):1905. doi: 10.3390/healthcare13151905.
This study aimed to evaluate the effect of nutritional education on nutritional knowledge, nutritional status, and quality of life in patients with liver cirrhosis. Thirty patients participated. At baseline, assessments were conducted to collect data on demographics, physical activity, anthropometric and biochemical measures, dietary habits, 24 h food intake, nutritional status, quality of life, and nutritional knowledge. Participants received a 30 min face-to-face nutritional education session by a registered dietitian, repeated after one month. A follow-up phone call was conducted one month later to reinforce the education. Final evaluations were completed one month after the call. A significant upward trend was detected in nutritional knowledge scores after the intervention period (from 7.4 ± 2.76 to 9.2 ± 3.45). The physical component of quality of life improved, while the mental component showed a slight decline. Dietary changes included reduced energy and protein intake among females and increased protein intake in males. In both genders, fat intake increased and carbohydrate intake decreased. Biochemical improvements were observed, including significant reductions in gamma-glutamyl transferase, aspartate aminotransferase, alanine aminotransferase, and triglycerides in females and alanine aminotransferase and gamma-glutamyl transferase in males. Structured nutritional education may improve nutritional knowledge, dietary behavior, and biochemical markers in cirrhosis patients. Longer follow-up durations may further enhance these improvements.
本研究旨在评估营养教育对肝硬化患者营养知识、营养状况及生活质量的影响。30名患者参与了研究。在基线期，进行评估以收集有关人口统计学、身体活动、人体测量学和生化指标、饮食习惯、24小时食物摄入量、营养状况、生活质量及营养知识的数据。参与者接受了由注册营养师进行的30分钟面对面营养教育课程，并在一个月后重复进行。一个月后进行了随访电话以强化教育。在电话随访一个月后完成最终评估。干预期后营养知识得分出现显著上升趋势（从7.4±2.76升至9.2±3.45）。生活质量的身体维度得到改善，而心理维度略有下降。饮食变化包括女性能量和蛋白质摄入量减少，男性蛋白质摄入量增加。在男女两性中，脂肪摄入量增加而碳水化合物摄入量减少。观察到生化指标有所改善，包括女性γ-谷氨酰转移酶、天冬氨酸氨基转移酶、丙氨酸氨基转移酶和甘油三酯显著降低，男性丙氨酸氨基转移酶和γ-谷氨酰转移酶显著降低。结构化营养教育可能改善肝硬化患者的营养知识、饮食行为和生化指标。更长的随访时间可能会进一步增强这些改善效果。
