He Yumei, Wang Zhiming, Wu Shiyan, Li Lu, Li Jiazhen, Zhang Yexing, Chen Boshi, Sun Xiaobin, Sun Chao, Wu Liping
North Sichuan Medical College, Nanchong, China.
Department of Gastroenterology, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu, China.
Front Nutr. 2024 Jul 18;11:1398690. doi: 10.3389/fnut.2024.1398690. eCollection 2024.
The development and advancement of malnutrition is associated not only with the progression of hepatic dysfunction, but also with cirrhosis-related complications. However, the prevalence of malnutrition reported in different studies varies widely due to differences in diagnostic methods and patient investigation settings. Therefore, we need to identify malnourished patients promptly and accurately. The purpose of this review was to compare the validity and reliability of nutritional screening tools and to select the most appropriate nutritional risk screening for patients with cirrhosis. We compared nutritional risk screening tools such as the Nutritional Risk Screening 2002 (NRS-2002), Malnutrition Universal Screening Tool (MUST), Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT) and Liver Disease Undernutrition Screening Tool (LDUST). Royal Free Hospital-Nutritional Prioritizing Tool (RFH-NPT) is more feasible to screen cirrhotic patients for nutritional risk, and is highly reproducible, considering the impact of sodium and water retention; so it is practical to screen cirrhotic patients via RFH-NPT for nutritional risk, subsequently, to evaluate the nutritional status of patients with nutritional risk via the Global Leadership Initiative on Malnutrition (GLIM) diagnostic criteria. L3-SMI (third lumbar-skeletal muscle index) can accurately define sarcopenia in cirrhotic patients and also be used for clinical nutritional status assessment.
营养不良的发生和进展不仅与肝功能障碍的进展有关,还与肝硬化相关并发症有关。然而,由于诊断方法和患者调查背景的差异,不同研究报告的营养不良患病率差异很大。因此,我们需要及时、准确地识别营养不良患者。本综述的目的是比较营养筛查工具的有效性和可靠性,并为肝硬化患者选择最合适的营养风险筛查方法。我们比较了营养风险筛查工具,如2002年营养风险筛查(NRS - 2002)、营养不良通用筛查工具(MUST)、皇家自由医院 - 营养优先排序工具(RFH - NPT)和肝病营养不良筛查工具(LDUST)。考虑到钠水潴留的影响,皇家自由医院 - 营养优先排序工具(RFH - NPT)对肝硬化患者进行营养风险筛查更可行,且具有高度可重复性;因此,通过RFH - NPT对肝硬化患者进行营养风险筛查是可行的,随后,通过全球营养不良领导倡议(GLIM)诊断标准评估有营养风险患者的营养状况。L3 - SMI(第三腰椎骨骼肌指数)可以准确界定肝硬化患者的肌肉减少症,也可用于临床营养状况评估。