Suppr超能文献

乳腺癌患者的生物电阻抗评估:综合疗法对细胞内环境稳定影响的病例报告

Bioelectrical Impedance Assessment in a Patient with Breast Cancer: A Case Report on the Effect of Integrative Therapies on Cellular Homeostasis.

作者信息

Marino Graziella, Pace Giovanni, Sabato Lucia, Sichetti Marzia, Mecca Marisabel

机构信息

Unit of Breast Cancer, Centro di Riferimento Oncologico della Basilicata (IRCCS-CROB), 85028 Rionero in Vulture, Italy.

Associazione AGATA OdV ETS, 75015 Marconia di Pisticci, Italy.

出版信息

Nutrients. 2025 Jul 30;17(15):2506. doi: 10.3390/nu17152506.

Abstract

: Since breast cancer (BC) survival rates have increased to 91% at 5 years and 80% at 15 years postdiagnosis, there is a growing awareness of the importance of addressing the long-term well-being of patients. Consequently, integrative oncology, which combines standard therapies with complementary approaches (nutrition, mind-body practices, and lifestyle modifications), has emerged as a patient-centred model aimed at improving symptom management, treatment adherence, and overall quality of life (QoL). This study aims to demonstrate how integrative therapies can benefit body composition, phase angle, and fluid and electrolyte balance through bioelectrical impedance analysis (BIA). : This study considers a patient who underwent BC surgery and was enrolled in the AMICO clinic for anamnesis, as well as their oncological pathology data, assessment of QoL, and BIA. The breast surgeon specialising in integrative oncology therapies prescribed the patient curcumin and polydatin, moderate physical activity, a balanced diet, and Qigong sessions. The patient underwent monitoring through haematochemical analysis, BIA, and a QoL questionnaire, with follow-up every four months. : Between 4 and 12 months, fat mass (FM) and body mass index (BMI) markedly decreased, whereas fat-free mass (FFM), total body water (TBW), and skeletal muscle mass (SMM) increased progressively. Moreover, the improvements in the Na/K ratio and phase angle (PhA) suggest a shift toward better electrolyte and fluid balance and enhanced cellular integrity and membrane function. Equally outstanding were her psychological benefits in terms of mood, sleep, anxiety, and melancholy. : Patient progress in body composition, metabolic function, pain management, and psychological status measured during the 12-month follow-up demonstrates the potential benefits of an integrative approach to supportive cancer care.

摘要

由于乳腺癌(BC)患者确诊后5年生存率已提高到91%,15年生存率提高到80%,人们越来越意识到关注患者长期健康的重要性。因此,整合肿瘤学应运而生,它将标准疗法与补充疗法(营养、身心锻炼和生活方式改变)相结合,是一种以患者为中心的模式,旨在改善症状管理、治疗依从性和整体生活质量(QoL)。本研究旨在通过生物电阻抗分析(BIA)证明整合疗法如何有益于身体成分、相位角以及体液和电解质平衡。

本研究纳入了一名接受过乳腺癌手术并在AMICO诊所进行问诊的患者,以及其肿瘤病理学数据、生活质量评估和生物电阻抗分析结果。专门从事整合肿瘤学治疗的乳腺外科医生为该患者开了姜黄素和虎杖苷,建议其适度进行体育活动、保持均衡饮食并参加气功课程。通过血液化学分析、生物电阻抗分析和生活质量问卷对患者进行监测,每四个月进行一次随访。

在4至12个月期间,脂肪量(FM)和体重指数(BMI)显著下降,而无脂肪量(FFM)、总体水(TBW)和骨骼肌量(SMM)则逐渐增加。此外,钠/钾比值和相位角(PhA)的改善表明电解质和体液平衡向更好的方向转变,细胞完整性和膜功能增强。同样显著的是,她在情绪、睡眠、焦虑和忧郁方面获得了心理益处。

在12个月的随访期间对患者身体成分、代谢功能、疼痛管理和心理状态的进展进行的测量表明,综合方法在支持性癌症护理方面具有潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4de6/12348733/eea138b1f295/nutrients-17-02506-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验