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美容医学手术的眼科并发症:一项叙述性综述。

Ophthalmological Complications of Aesthetic Medicine Procedures: A Narrative Review.

作者信息

De-Pablo-Gómez-de-Liaño Lucía, Ly-Yang Fernando, Burgos-Blasco Bárbara, Fernández-Vigo José Ignacio

机构信息

Department of Ophthalmology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.

Department of Immunology, Ophthalmology and ENT, Faculty of Optics, Complutense University of Madrid, 28037 Madrid, Spain.

出版信息

J Clin Med. 2025 Jul 31;14(15):5399. doi: 10.3390/jcm14155399.

Abstract

Minimally invasive cosmetic procedures, such as dermal fillers, botulinum toxin injections, autologous fat grafting, intense pulsed light (IPL) treatments, and platelet-rich plasma (PRP) treatments, are increasingly popular worldwide due to their convenience and aesthetic benefits. While generally considered safe, these procedures can result in rare but serious ophthalmological complications. The most catastrophic adverse events include central retinal artery occlusion and ischemic optic neuropathy, which may lead to irreversible vision loss. Other complications include diplopia, ptosis, dry eye, and orbital cellulitis, with varying degrees of severity and reversibility. Awareness of potential ocular risks, appropriate patient selection, and adherence to safe injection techniques are crucial for preventing complications. This narrative review summarizes the incidence, mechanisms, clinical features, risk factors, diagnostic approaches, and management strategies of ocular complications associated with aesthetic medical procedures. A narrative literature review was conducted, emphasizing data from clinical studies, case series, and expert consensus published between 2015 and 2025. Special attention is given to anatomical danger zones, the pathophysiological pathways of filler embolization, and the roles of hyaluronidase and hyperbaric oxygen therapy in acute management. Although many complications are self-limited or reversible, prompt recognition and intervention are critical to prevent permanent sequelae. The increasing prevalence of these procedures demands enhanced education, informed consent, and interdisciplinary collaboration between aesthetic providers and ophthalmologists.

摘要

微创美容手术,如注射填充剂、肉毒杆菌毒素注射、自体脂肪移植、强脉冲光(IPL)治疗和富血小板血浆(PRP)治疗,因其便利性和美学效果在全球范围内越来越受欢迎。虽然通常被认为是安全的,但这些手术可能会导致罕见但严重的眼科并发症。最严重的不良事件包括视网膜中央动脉阻塞和缺血性视神经病变,这可能导致不可逆转的视力丧失。其他并发症包括复视、上睑下垂、干眼和眼眶蜂窝织炎,其严重程度和可逆性各不相同。认识潜在的眼部风险、进行适当的患者选择以及遵循安全的注射技术对于预防并发症至关重要。本叙述性综述总结了与美容医疗手术相关的眼部并发症的发生率、机制、临床特征、危险因素、诊断方法和管理策略。进行了叙述性文献综述,重点关注2015年至2025年间发表的临床研究、病例系列和专家共识中的数据。特别关注解剖学危险区域、填充剂栓塞的病理生理途径以及透明质酸酶和高压氧治疗在急性处理中的作用。尽管许多并发症是自限性或可逆的,但及时识别和干预对于预防永久性后遗症至关重要。这些手术的日益普及需要加强教育、知情同意,并促进美容医疗服务提供者与眼科医生之间的跨学科合作。

本文引用的文献

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