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心房颤动与癌症:病理生理机制及临床意义

Atrial Fibrillation and Cancer: Pathophysiological Mechanism and Clinical Implications.

作者信息

Mauriello Alfredo, Correra Adriana, Quagliariello Vincenzo, Iovine Martina, Di Micco Pierpaolo, Imbalzano Egidio, Giallauria Francesco, Giordano Antonio, Russo Vincenzo, D'Andrea Antonello, Maurea Nicola

机构信息

Division of Cardiology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Napoli, Italy.

Intensive Cardiac Care Unit, "San Giuseppe Moscati" Hospital, ASL Caserta, 81031 Aversa, Italy.

出版信息

J Clin Med. 2025 Aug 7;14(15):5600. doi: 10.3390/jcm14155600.

DOI:10.3390/jcm14155600
PMID:40807221
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12347568/
Abstract

Atrial fibrillation is the most frequent arrhythmia in elderly subjects. Cancer currently represents one of the most important causes of mortality and morbidity in the world. Often, the two pathologies coexist. Several pathophysiological mechanisms can lead to an increased risk of atrial fibrillation and cancer. Additionally, the same therapies used for cancer can increase the risk of developing atrial fibrillation. Our review aims to describe the pathophysiological mechanisms that promote the development of atrial fibrillation in cancer patients and explain the therapeutic opportunities and challenges of treating atrial fibrillation in patients with cancer.

摘要

心房颤动是老年患者中最常见的心律失常。癌症是目前全球最重要的死亡和发病原因之一。这两种疾病常常并存。多种病理生理机制可导致心房颤动和癌症的风险增加。此外,用于治疗癌症的相同疗法也会增加发生心房颤动的风险。我们的综述旨在描述促使癌症患者发生心房颤动的病理生理机制,并解释治疗癌症患者心房颤动的治疗机会和挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212b/12347568/31c52f0da2e4/jcm-14-05600-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212b/12347568/31c52f0da2e4/jcm-14-05600-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/212b/12347568/31c52f0da2e4/jcm-14-05600-g001.jpg

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Antioxidants (Basel). 2025 May 20;14(5):612. doi: 10.3390/antiox14050612.
2
Serum Lipids, Inflammation, and the Risk of Atrial Fibrillation: Pathophysiological Links and Clinical Evidence.血清脂质、炎症与心房颤动风险:病理生理联系及临床证据
J Clin Med. 2025 Feb 28;14(5):1652. doi: 10.3390/jcm14051652.
3
Management of thrombocytopenia and anticoagulant therapy in patients with hematological malignancy on chemotherapy: a binational prospective study (TAT study).
血液系统恶性肿瘤化疗患者血小板减少症的管理及抗凝治疗:一项双边前瞻性研究(TAT研究)
J Thromb Thrombolysis. 2025 Jun;58(5):646-656. doi: 10.1007/s11239-025-03085-3. Epub 2025 Mar 17.
4
Abelacimab versus Rivaroxaban in Patients with Atrial Fibrillation.阿贝西单抗与利伐沙班治疗心房颤动患者的比较
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Diagnostics (Basel). 2024 Dec 24;15(1):7. doi: 10.3390/diagnostics15010007.
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Antioxidants (Basel). 2024 Jul 2;13(7):806. doi: 10.3390/antiox13070806.