Zhu Jing, Wang Hua-Fen, Zhang Jia-Xiang, Wang Man, Zhuang Yu-Wei, Suo Zhi-Guang, He Ye-Wu, Zhang Yan-Chang, Wei Min, Zhang Hai-Yan
Henan Key Laboratory of Cereal and Oil Food Safety Inspection and Control, College of Food Science and Technology, Henan University of Technology, Zhengzhou 450001, China.
High & New Technology Research Center of Henan Academy of Sciences, No. 56 Hongzhuan Road, Zhengzhou 450002, China.
Molecules. 2025 Aug 7;30(15):3309. doi: 10.3390/molecules30153309.
Cobalt, a rare element in the Earth's crust, is widely used in industries due to its hardness and antioxidant properties. It also plays a vital role in physiological functions, being a key component of vitamin B. However, excessive cobalt intake can cause health issues. Detecting cobalt ions, especially Co, in food is crucial due to potential contamination from various sources. Fluorescent probes offer high sensitivity, selectivity, a rapid response, and ease of use, making them ideal for the accurate and efficient recognition of Co in complex samples. In this context, a highly selective fluorescent probe, 2,2'-((3-(1H-benzo[d]imidazol-2-yl)-1,2-phenylene) bis(oxy)) bis(N-(quinolin-8-yl) acetamide) (), was synthesized using chloroacetyl chloride, 8-aminoquinoline, 2,3-dihydroxybenzaldehyde, and benzidine as raw materials for the recognition of Co. Probe can exhibit fluorescence alone in DMF. However, as the concentration of Co increased, Photoinduced Electron Transfer (PET) occurred, which quenched the original fluorescence of the probe. Probe shows better selectivity for Co than other ions with high sensitivity (detection limit: 3.56 μmol L), and the reaction reaches equilibrium within 30 min.
钴是地壳中一种稀有元素，因其硬度和抗氧化性能而在工业中广泛使用。它在生理功能中也起着至关重要的作用，是维生素B的关键成分。然而，过量摄入钴会引发健康问题。由于食物可能受到各种来源的污染，检测食品中的钴离子，尤其是Co²⁺至关重要。荧光探针具有高灵敏度、高选择性、响应迅速和使用方便等优点，使其成为在复杂样品中准确高效识别Co²⁺的理想选择。在此背景下，以氯乙酰氯、8-氨基喹啉、2,3-二羟基苯甲醛和联苯胺为原料合成了一种高选择性荧光探针2,2'-((3-(1H-苯并[d]咪唑-2-基)-1,2-亚苯基)双(氧基))双(N-(喹啉-8-基)乙酰胺)（）用于识别Co²⁺。探针在N,N-二甲基甲酰胺（DMF）中单独就能发出荧光。然而，随着Co²⁺浓度的增加，发生了光诱导电子转移（PET），淬灭了探针原来的荧光。探针 对Co²⁺的选择性优于其他离子，具有高灵敏度（检测限：3.56 μmol·L⁻¹），并且反应在30分钟内达到平衡。
