局部麻醉药的研究。第79部分：烷氧基甲基氨基甲酸哌啶乙酯的物理化学性质。
Study of local anesthetics. Part 79: Physico-chemical properties of piperidinoethyl esters of alkoxymethylcarbanilic acids.
作者信息
Kopecký F, Pesák M, Macek J, Borovanský A
出版信息
Pharmazie. 1985 Aug;40(8):572-3.
PMID:4080807
Abstract
Partition coefficients, pH's of turbidity, surface tensions of aqueous solutions, UV spectra and RF values of the adsorption TLC of the salts of 9 piperidinoethylesters of alkoxymethylcarbanilic acids were measured. The surface and infiltration local anesthetic activities of the compounds were correlated with the determined physico-chemical parameters.
摘要
测定了9种烷氧基甲基氨基苯甲酸哌啶乙酯盐的分配系数、浊度pH值、水溶液表面张力、紫外光谱以及吸附薄层色谱的比移值。将这些化合物的表面麻醉和浸润麻醉活性与所测定的物理化学参数进行了关联。
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