Snowden J M, Cliff W J
Q J Exp Physiol. 1985 Oct;70(4):539-48. doi: 10.1113/expphysiol.1985.sp002940.
The tension generated in vitro by samples of granulation tissue taken from wounds at various times after wounding has been measured. Throughout the period when in vivo contraction was occurring with a constant linear rate of movement of the wound margins the in vitro tension produced by samples of the granulation tissue remained constant at approximately 80 mg/mm2. With cessation of contraction in vivo, the tension generated by the granulation tissue fell to 40 mg/mm2. Morphometric studies demonstrated that total cellularity paralleled the tension developed. However, the decrease in cellularity preceded by approximately 4 d the decrease in the tension developed. Strong correlation between the rate of contraction and the maximum thickness of the granulation tissue was demonstrated.
已对在创伤后不同时间从伤口获取的肉芽组织样本在体外产生的张力进行了测量。在体内伤口边缘以恒定线性速率移动而发生收缩的整个期间，肉芽组织样本产生的体外张力在约80mg/mm²保持恒定。随着体内收缩停止，肉芽组织产生的张力降至40mg/mm²。形态计量学研究表明，总细胞数与所产生的张力平行。然而，细胞数的减少比所产生张力的减少提前约4天。已证实收缩速率与肉芽组织的最大厚度之间存在强相关性。
