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南非一家三级医院阑尾切除术的临床病理谱及结果:延迟就诊的持续影响

Clinicopathological spectrum and outcome of appendicectomy at a South African tertiary hospital: continuing impact of delayed presentation.

作者信息

Simelane P B, Kader S S, Madiba T E

机构信息

Department of Surgery, University of KwaZulu-Natal, Durban.

出版信息

Afr Health Sci. 2024 Jun;24(2):365-374. doi: 10.4314/ahs.v24i2.37.

Abstract

INTRODUCTION

Appendicitis is a common surgical emergency, associated with significant morbidity and mortality.

AIM

To describe the clinicopathological spectrum and outcome of appendicitis in our setting.

METHODS

Retrospective descriptive chart review of patients undergoing surgery for appendicitis over two study periods (Group A: 2010-2012 and Group B: 2016-2018). Data collected included demographics, clinical presentation, operative findings and outcome.

RESULTS

There were 229 patients in Group A [median age 24 (IQR 18-32) years] and 145 in Group B [median age 28 (IQR 20-36) years]. Median pre-hospital delay was 3 days for Group A 3 (IQR 2-4) and 1 day for Group B 1 (IQR 1-2). Complicated appendicitis occurred in 69 (30.1%) and 37 (25.5%) patients in Group A and B respectively. Post-operative complication rate was 18.3% and 8.3 % in Groups A and B respectively. Postoperative mortality in Group A was 3.5% and 2 1% for Group B. Delay in presentation was associated with increased complicated appendicitis.

CONCLUSION

Complicated appendicitis was seen in one third of the patients in both groups. Delay in presentation persists in our setting and it is associated with complicated appendicitis, which carries an increased morbidity and mortality.

摘要

引言

阑尾炎是一种常见的外科急症,会导致较高的发病率和死亡率。

目的

描述我们医院阑尾炎的临床病理特征及治疗结果。

方法

对两个研究时间段(A组:2010 - 2012年;B组:2016 - 2018年)接受阑尾炎手术的患者进行回顾性描述性图表分析。收集的数据包括人口统计学资料、临床表现、手术所见及治疗结果。

结果

A组有229例患者[中位年龄24(四分位间距18 - 32)岁],B组有145例患者[中位年龄28(四分位间距20 - 36)岁]。A组院前延迟时间中位数为3天(四分位间距2 - 4),B组为1天(四分位间距1 - 2)。A组和B组分别有69例(30.1%)和37例(25.5%)患者发生复杂性阑尾炎。A组和B组术后并发症发生率分别为18.3%和8.3%。A组术后死亡率为3.5%,B组为2.1%。就诊延迟与复杂性阑尾炎的增加有关。

结论

两组中三分之一的患者患有复杂性阑尾炎。在我们医院,就诊延迟情况仍然存在,且与复杂性阑尾炎相关,后者会导致更高的发病率和死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a247/12341187/a00ba45bf263/AFHS2402-0365Fig1.jpg

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