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本文引用的文献

1
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2
Basic Principles of Rotational Thromboelastometry (ROTEM) and the Role of ROTEM-Guided Fibrinogen Replacement Therapy in the Management of Coagulopathies.旋转血栓弹力图(ROTEM)的基本原理及ROTEM指导的纤维蛋白原替代疗法在凝血障碍管理中的作用
Diagnostics (Basel). 2023 Oct 16;13(20):3219. doi: 10.3390/diagnostics13203219.
3
Viscoelastic testing: Critical appraisal of new methodologies and current literature.黏弹性测试:新方法和现有文献的批判性评价。
Int J Lab Hematol. 2023 Oct;45(5):643-658. doi: 10.1111/ijlh.14144. Epub 2023 Aug 9.
4
Guided blood transfusion of trauma patients with rotational thromboelastometry: a single-center cohort study.运用旋转血栓弹力描记术指导创伤患者输血:一项单中心队列研究。
World J Emerg Surg. 2023 Jul 1;18(1):40. doi: 10.1186/s13017-023-00508-5.
5
Thromboelastometry-guided haemostatic resuscitation in severely injured patients: a propensity score-matched study.血栓弹力描记术指导下严重创伤患者的止血复苏:一项倾向评分匹配研究。
Crit Care. 2023 Apr 13;27(1):141. doi: 10.1186/s13054-023-04421-w.
6
Viscoelastic coagulation testing in Neonatal Intensive Care Units: advantages and pitfalls in clinical practice.新生儿重症监护病房中黏弹性凝血检测的临床应用:优势与陷阱
Blood Transfus. 2023 Nov 13;21(6):538-548. doi: 10.2450/2023.0203-22.
7
Role of Viscoelastic and Conventional Coagulation Tests for Management of Blood Product Replacement in the Bleeding Patient.黏弹性和常规凝血试验在出血患者血液制品替代管理中的作用。
Semin Thromb Hemost. 2022 Oct;48(7):785-795. doi: 10.1055/s-0042-1756192. Epub 2022 Sep 29.
8
Viscoelastic Hemostatic Assays: A Primer on Legacy and New Generation Devices.粘弹性止血检测:传统与新一代设备入门指南
J Clin Med. 2022 Feb 7;11(3):860. doi: 10.3390/jcm11030860.
9
Pathophysiology of Trauma-Induced Coagulopathy.创伤性凝血病的病理生理学。
Transfus Med Rev. 2021 Oct;35(4):80-86. doi: 10.1016/j.tmrv.2021.07.004. Epub 2021 Aug 29.
10
TEG and ROTEM Traces: Clinical Applications of Viscoelastic Coagulation Monitoring in Neonatal Intensive Care Unit.血栓弹力图(TEG)和旋转血栓弹力图(ROTEM)曲线:黏弹性凝血监测在新生儿重症监护病房的临床应用
Diagnostics (Basel). 2021 Sep 7;11(9):1642. doi: 10.3390/diagnostics11091642.

创伤相关凝血病中血栓弹力图与旋转血栓弹力测定法的比较评估

Comparative Assessment of Thromboelastography and Rotational Thromboelastometry in Trauma-Related Coagulopathy.

作者信息

Sta Ines Mars Christian A, Khalid Usman I, Shah Muhmmad H

机构信息

Medical Education and Emergency Medicine, University Hospital Coventry, Coventry, GBR.

Trauma and Orthopaedics, Royal Victoria Hospital, Belfast, GBR.

出版信息

Cureus. 2025 Jul 14;17(7):e87890. doi: 10.7759/cureus.87890. eCollection 2025 Jul.

DOI:10.7759/cureus.87890
PMID:40809622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12345383/
Abstract

Background Trauma-induced coagulopathy (TIC) has a crucial impact on the outcome and death rate in people suffering from trauma. This study aimed to evaluate the speed, reliability, and treatment decisions of thromboelastography (TEG) and rotational thromboelastometry (ROTEM) use in emergency trauma cases. Methods This prospective observational study was used to investigate 60 trauma patients with suspected coagulopathy. TEG and ROTEM measured clot initiation, its formation, strength, and lysis, along with the more common lab coagulation tests (prothrombin time, activated partial thromboplastin time, and platelet counts). All tests were performed to compare blood transfusion status, fibrinogen, antifibrinolytic use, and the timing of surgery. To assess the comparisons, Student's t-test and chi-square analysis were both carried out with a significant p-value of <0.05. Results Both TEG and ROTEM effectively assessed coagulopathy. ROTEM measured results faster, with a mean time of 24 minutes, compared to TEG with a mean time of 31 minutes (p<0.001). It was found that ROTEM resulted in quicker clotting time and clot formation (both p-values were 0.01 and 0.03). Patients under ROTEM treatment were treated and operated on sooner than those in the TEG group. However, there were no significant variations found in transfusion and fibrinogen use in TEG and ROTEM groups. Conclusion Both TEG and ROTEM can give reliable information about trauma patients' coagulopathy. With ROTEM, the results were obtained rapidly, and doctors were able to make clinical decisions faster in critical care cases. Even though clot test results were slightly different, both types of assays helped with better resuscitation for each patient.

摘要

背景 创伤性凝血病(TIC)对创伤患者的预后和死亡率有着至关重要的影响。本研究旨在评估在急诊创伤病例中使用血栓弹力图(TEG)和旋转血栓弹力测定法(ROTEM)的速度、可靠性及治疗决策。方法 本前瞻性观察性研究用于调查60例疑似凝血病的创伤患者。TEG和ROTEM测量凝血起始、形成、强度和溶解情况,以及更常见的实验室凝血检测(凝血酶原时间、活化部分凝血活酶时间和血小板计数)。所有检测均用于比较输血状态、纤维蛋白原、抗纤溶药物的使用及手术时机。为评估比较结果,采用了学生t检验和卡方分析,显著性p值<0.05。结果 TEG和ROTEM均能有效评估凝血病。ROTEM测量结果更快,平均时间为24分钟,而TEG的平均时间为31分钟(p<0.001)。发现ROTEM导致凝血时间和凝块形成更快(p值均为0.01和0.03)。接受ROTEM治疗的患者比TEG组患者接受治疗和手术的时间更早。然而,TEG组和ROTEM组在输血和纤维蛋白原使用方面未发现显著差异。结论 TEG和ROTEM均能提供有关创伤患者凝血病的可靠信息。使用ROTEM时,结果获取迅速,医生能够在重症监护病例中更快地做出临床决策。尽管凝血检测结果略有不同,但两种检测方法都有助于为每位患者进行更好的复苏。