Zheng Hai-Bo, Yu Chang-Qing, Ji Qiu-Ming, Liu Bing, Liu Yuan-Yuan, Chen Hai-Ying, Cao Yu-Lin, Gong Ji-Fen, Chen Ting
Department of Psychiatry, Wuhan Wudong Hospital, The Second Mental Hospital of Wuhan, Wuhan, Hubei, China.
School of Public Health, Medical School, Wuhan University of Science and Technology, Wuhan, Hubei, China.
Front Psychiatry. 2025 Jul 30;16:1566356. doi: 10.3389/fpsyt.2025.1566356. eCollection 2025.
In China, the coexistence of mental illness and tobacco dependence is a major public health issue. With around 300 million smokers and over one million annual smoking-related deaths, the resulting social and economic burdens are considerable.
A cross-sectional study design was employed to gather data on tobacco use, readiness to quit smoking, and nicotine dependence from a random sample of 738 patients diagnosed with severe mental illness. Data analysis, which included descriptive statistics and multivariate logistic regression analysis, was conducted via SPSS 27.0.
The findings revealed that the smoking prevalence among patients with severe mental illness was 52.03%, significantly higher than that of the general population. Multifactorial logistic regression analysis indicated that male gender(OR=10.041, 95% CI: 6.499-15.513), Han ethnicity(OR=3.263, 95% CI: 1.053-10.108), worse economic status (OR=2.540, 95% CI: 1.424-4.529), family history of smoking (OR=6.474, 95% CI: 4.211-9.952), outpatient status(OR=2.294, 95% CI: 1.433-3.674), family history of mental illness (OR=1.756, 95% CI: 1.129-2.731), history of drug exposure(OR=2.074, 95% CI: 1.244-3.458), and history of alcohol consumption(OR=5.216, 95% CI: 3.037-8.960) were independent risk factors for smoking in this patient group. Furthermore, there were significant differences in nicotine dependence levels across different psychiatric diagnoses, with patients diagnosed with schizophrenia and bipolar disorder exhibiting higher levels of nicotine dependence compared to those with paranoid disorder who showed lower levels.
The study elucidates the complex nature and critical determinants of tobacco use patterns among individuals with severe mental illness, providing a solid scientific foundation for developing targeted intervention strategies.
ChiCTR2400088459.
在中国，精神疾病与烟草依赖并存是一个重大的公共卫生问题。中国约有3亿烟民，每年有超过100万人死于与吸烟相关的疾病，由此产生的社会和经济负担相当可观。
采用横断面研究设计，从738例被诊断为严重精神疾病的患者中随机抽样，收集烟草使用、戒烟意愿和尼古丁依赖的数据。通过SPSS 27.0进行数据分析，包括描述性统计和多因素逻辑回归分析。
研究结果显示，严重精神疾病患者的吸烟率为52.03%，显著高于普通人群。多因素逻辑回归分析表明，男性（OR=10.041，95%CI：6.499-15.513）、汉族（OR=3.263，95%CI：1.053-10.108）、经济状况较差（OR=2.540，95%CI：1.424-4.529）、吸烟家族史（OR=6.474，95%CI：4.211-9.952）、门诊状态（OR=2.294，95%CI：1.433-3.674）、精神疾病家族史（OR=1.756，95%CI：1.129-2.731）、药物暴露史（OR=2.074，95%CI：1.244-3.458）和饮酒史（OR=5.216，95%CI：3.037-8.960）是该患者群体吸烟的独立危险因素。此外，不同精神疾病诊断的尼古丁依赖水平存在显著差异，被诊断为精神分裂症和双相情感障碍的患者尼古丁依赖水平高于偏执性障碍患者，后者尼古丁依赖水平较低。
该研究阐明了严重精神疾病患者烟草使用模式的复杂性和关键决定因素，为制定有针对性的干预策略提供了坚实的科学依据。
ChiCTR2400088459。
