量子成像在生物学中的应用。

Application of quantum imaging in biology.

作者信息

Lotfipour Hoda, Sobhani Hassan, Dejpasand Mohamad Taghi, Sasani Ghamsari Morteza

机构信息

Photonics and Quantum Technologies Research School, Nuclear Science and Technology Research Institute, Tehran, 11155-3486, Iran.

出版信息

Biomed Opt Express. 2025 Jul 23;16(8):3349-3377. doi: 10.1364/BOE.566801. eCollection 2025 Aug 1.

Abstract

Application of quantum imaging in biology In biology, one of the main challenges is achieving a balance between high precision and minimal invasiveness in measurements. With cutting-edge techniques, the primary limitations to experimental accuracy often stem not from device-related noise but from fundamental physical constraints. Since nature is the underlying source of these constraints, it makes sense to go to quantum mechanics, the most basic theory of matter, for a solution. Improved measurement performance may be possible through the application of quantum effects, particularly those pertaining to coherence. It offers useful tools that, at the very least, offer interesting technical solutions even when they don't fully display cohesive behaviors. One of the primary applications of quantum technologies is quantum metrology, which uses the non-classical state of light to measure physical properties with great resolution and sensitivity. For biological applications, the quantum state of light may be utilized for precision enhancement and quantum noise reduction. This explains how quantum metrology, and particularly quantum imaging, can be used to enhance picture quality, measure shifts in quantum scales in biological systems, and boost imaging precision and resolution using quantum light sources, devices, and protocols. In this study, we give a summary of the possible uses of quantum technology in biology and medicine. This review presents a comprehensive overview of how quantum technologies can be applied in biology and medicine. It also explores the latest developments in quantum biological imaging, quantum microscopy, and quantum materials, while discussing the challenges and opportunities these emerging technologies bring.

摘要

量子成像在生物学中的应用 在生物学领域,主要挑战之一是在测量中实现高精度与最小侵入性之间的平衡。借助前沿技术,实验精度的主要限制往往并非源于与设备相关的噪声,而是源于基本的物理约束。由于自然是这些约束的潜在来源,因此求助于量子力学这一最基本的物质理论来寻求解决方案是合理的。通过应用量子效应,特别是与相干性相关的效应,有可能提高测量性能。它提供了有用的工具,即使这些工具不能完全展现凝聚行为,至少也能提供有趣的技术解决方案。量子技术的主要应用之一是量子计量学,它利用光的非经典状态以极高的分辨率和灵敏度测量物理性质。对于生物学应用而言,光的量子态可用于提高精度和降低量子噪声。这就解释了量子计量学,尤其是量子成像,如何能够用于提高图像质量、测量生物系统中量子尺度的变化,以及利用量子光源、设备和协议提高成像精度和分辨率。在本研究中,我们总结了量子技术在生物学和医学中的可能用途。这篇综述全面概述了量子技术如何应用于生物学和医学。它还探讨了量子生物成像、量子显微镜和量子材料的最新进展,同时讨论了这些新兴技术带来的挑战和机遇。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53a8/12339294/9e7d8d7c7716/boe-16-8-3349-g001.jpg

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