Dudeffant P, Manier G, Gbikpi-Benissan G, Cardinaud J P
Rev Mal Respir. 1985;2(3):145-50.
60 patients were studied with severe chronic respiratory failure (IRC) and a permanent tracheostomy treated with domiciliary ventilation (VADT). The study commenced from the time of the tracheostomy and included length of survival (by the actuarial method) quality of life, subjectively and objectively (progress of blood gases in a stable clinical state and cumulative length of periods in hospital). Factors influencing the decision for tracheostomy and VADT were examined. Restrictive cases benefitted from the technique as much from the improved quality of life as from the duration of survival (77% at 5 years). Patients with an obstructive or mixed pattern had a 5 years survival of 73% after the first episode of acute or chronic respiratory failure which was 73% better than comparable patients given neither a tracheostomy nor oxygen therapy. The five years survival of 42% on VADT in our series compares favourably with the main series published. In our opinion the improved survival in these patients (which tends to rejoin that of the general population) and the improved quality of life justifies the use of this treatment in severe obstructive IRC, despite a greater demand and cost of this treatment than those with a restrictive defect.
对60例患有严重慢性呼吸衰竭(IRC)且接受家庭通气治疗(VADT)并进行永久性气管造口术的患者进行了研究。该研究从气管造口术时开始,包括生存时间(采用精算方法)、主观和客观的生活质量(稳定临床状态下的血气进展以及住院累计时长)。研究了影响气管造口术和VADT决策的因素。限制性病例从该技术中获益,生活质量的改善和生存时长均有所受益(5年时为77%)。阻塞性或混合型患者在首次急性或慢性呼吸衰竭发作后的5年生存率为73%,这比未接受气管造口术和氧疗的可比患者高出73%。我们系列中接受VADT治疗的患者5年生存率为42%,与已发表的主要系列研究相比具有优势。我们认为,这些患者生存率的提高(趋向于接近普通人群)和生活质量的改善证明了在严重阻塞性IRC中使用这种治疗方法的合理性,尽管这种治疗比限制性缺陷患者的需求更大、成本更高。