Yoshihara S, Nakagawa M, Suda H
Res Vet Sci. 1985 Nov;39(3):383-4.
Immature worms were recovered from the liver parenchyma of rats which received extracts of metacercariae or adult worms of Fasciola gigantica, after challenge infection. When resistance was assessed by counting the number of immature worms, exposure of the animals to extracts of these two stages of the flukes conferred a significant degree of protection against challenge with F gigantica metacercariae. Rats given the extract of metacercariae were more resistant to infection than rats immunised with the extract of adult worms.
在攻击感染后，从未成熟虫体提取物或巨片形吸虫成虫提取物的大鼠肝脏实质中回收未成熟虫体。当通过计算未成熟虫体数量来评估抵抗力时，动物接触这两个阶段吸虫的提取物可提供显著程度的保护，使其免受巨片形吸虫囊蚴的攻击。给予囊蚴提取物的大鼠比用成虫提取物免疫的大鼠对感染更具抵抗力。
