Weisberg J A, Rustioni A
Exp Brain Res. 1977 Jul 15;28(5):521-8. doi: 10.1007/BF00236474.
Corticals cells projecting to the dorsal column nuclei (DCN) of Rhesus monkeys have been identified after unilateral or bilateral injection of horseradish peroxidase (HRP) into the dorsal medulla. HRP-positive neurons identifiable as the source of cortico-DCN projections were pyramidal cells in layer V whose largest diameters ranged from 12--31 micron. Cortico-DCN neurons were concentrated in the trunk, fore- and hindlimb regions of area 4 and of SI, and to a lesser extent in SII. This distribution is comparable to the topographical distribution of cortico-DCN neurons in cats. However, cortico-DCN neurons in monkeys are also numerous in at least part of the supplementary motor cortex and in area 5. The results suggest that cortical neurons in several different cytoarchitectonic areas may exert direct control upon cells in the DCN and that the functional role of cortic-DCN projections ought not be view as a simple "feedback" system.
在恒河猴的背髓单侧或双侧注射辣根过氧化物酶（HRP）后，已鉴定出投射到延髓背柱核（DCN）的皮质细胞。可鉴定为皮质 - DCN投射源的HRP阳性神经元是V层的锥体细胞，其最大直径范围为12 - 31微米。皮质 - DCN神经元集中在4区和SI区的躯干、前肢和后肢区域，在SII区的分布较少。这种分布与猫的皮质 - DCN神经元的地形分布相当。然而，猴子的皮质 - DCN神经元在至少部分辅助运动皮层和5区也很多。结果表明，几个不同细胞构筑区域的皮质神经元可能对DCN中的细胞施加直接控制，并且皮质 - DCN投射的功能作用不应被视为一个简单的“反馈”系统。
