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下肢血管创伤中自体移植物与人工合成移植物的比较:两例农村病例报告的经验教训

Native vs. synthetic grafts in lower extremity vascular trauma: Lessons from two rural case presentations.

作者信息

Darwis Patrianef, Suhartono Raden, Hidayat Nabila, Faruk Muhammad

机构信息

Division of Vascular and Endovascular Surgery, Department of Surgery, Faculty of Medicine, University of Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia.

出版信息

Int J Surg Case Rep. 2025 Sep;134:111785. doi: 10.1016/j.ijscr.2025.111785. Epub 2025 Aug 7.

Abstract

INTRODUCTION

Trauma to the extremities is a common injury that demands a comprehensive evaluation of vascular structures. Prompt identification and timely intervention improve clinical outcomes; severe injuries frequently lead to complications and potential limb loss. Revascularization delays greater than 8 h post-injury markedly increase amputation risk. This report describes successful management strategies for lower extremity vascular injuries by comparing native and synthetic graft applications.

CASE PRESENTATIONS

Two patients with lower extremity vascular injuries are detailed. Case 1: a 54-year-old female with blunt trauma to the right leg that resulted in femoropopliteal occlusion successfully underwent a saphenous vein graft (SVG) bypass. Case 2: a 28-year-old female presented 27 h post-road traffic collision with a left thigh injury and total transection of the superficial femoral artery. Revascularization was achieved via femoropopliteal extra-anatomic bypass using an expanded polytetrafluoroethylene (ePTFE) vascular graft. Both patients were discharged 2 weeks post-surgery with favorable outcomes.

CLINICAL DISCUSSION

Case 1 emphasizes the importance of prompt diagnosis and intervention. Case 2 demonstrates limb salvage potential despite delayed presentation. The choice between autologous SVGs (superior biocompatibility, long-term patency) and synthetic ePTFE grafts (readily available, higher re-occlusion risk) dictates postoperative management, particularly in terms of anticoagulation therapy.

CONCLUSIONS

This report illustrates successful open surgical bypasses for femoropopliteal occlusion and ruptured superficial femoral artery. It underscores the importance of timely intervention and differing postoperative management methods for autologous SVGs and synthetic ePTFE grafts. An algorithmic approach to diagnosis and treatment, alongside surgeon comprehension of therapeutic options, is paramount for optimal outcomes.

摘要

引言

四肢创伤是一种常见损伤,需要对血管结构进行全面评估。及时识别和适时干预可改善临床结局;严重损伤常导致并发症和肢体可能丧失。损伤后血运重建延迟超过8小时会显著增加截肢风险。本报告通过比较自体和人工血管移植物的应用,描述了下肢血管损伤的成功治疗策略。

病例介绍

详细介绍了两名下肢血管损伤患者。病例1:一名54岁女性,右腿钝器伤导致股腘动脉闭塞,成功接受了大隐静脉移植(SVG)搭桥手术。病例2:一名28岁女性在道路交通事故后27小时就诊,左大腿受伤,股浅动脉完全横断。通过使用膨体聚四氟乙烯(ePTFE)血管移植物进行股腘部解剖外搭桥实现了血运重建。两名患者均在术后2周出院,预后良好。

临床讨论

病例1强调了及时诊断和干预的重要性。病例2表明,尽管就诊延迟,但仍有保肢潜力。自体SVG(生物相容性好、长期通畅)和人工ePTFE移植物(易于获取、再闭塞风险较高)之间的选择决定了术后管理,尤其是在抗凝治疗方面。

结论

本报告阐述了股腘动脉闭塞和股浅动脉破裂的成功开放手术搭桥。它强调了及时干预以及自体SVG和人工ePTFE移植物不同术后管理方法的重要性。采用算法化的诊断和治疗方法,以及外科医生对治疗选择的理解,对于实现最佳结局至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e097/12391503/03ceddfc12a1/gr1.jpg

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