Postacchini F, Massobrio M
Spine (Phila Pa 1976). 1985 Jul-Aug;10(6):567-70.
Over a 2-year period, 92 patients were submitted as outpatients to lumbar myelography using lopamidol, a new nonionic water-soluble contrast medium. The incidence and severity of adverse reactions associated with myelography in these cases were compared with those in 116 patients who underwent lopamidol myelography as inpatients. The hospitalized patients received 10 ml, and the outpatients 8 or 10 ml of contrast medium (300 mg l/ml). The severity of complications was graded as very mild, mild, moderate, or severe. The complication rate was 37% in the hospitalized patients and 40% in the outpatients. Adverse reactions, mostly in the form of headache, were very mild in approximately two thirds of cases in each group, and moderate or severe in 15% of the inpatients and 24% of the outpatients presenting complications. The incidence of moderate or severe reactions was lower in the outpatients receiving 8 ml of contrast medium compared with those given 10 ml. lopamidol lumbar myelography performed on an outpatient basis is a safe procedure. The outpatient regimen considerably reduces the cost of myelography and indirectly increases the availability of beds in orthopaedic and neurologic units.
在两年期间，92例患者作为门诊病人接受了使用新型非离子水溶性造影剂碘帕醇的腰椎脊髓造影。将这些病例中与脊髓造影相关的不良反应的发生率和严重程度与116例住院接受碘帕醇脊髓造影的患者进行了比较。住院患者接受10毫升造影剂，门诊患者接受8或10毫升造影剂（300毫克碘/毫升）。并发症的严重程度分为非常轻微、轻微、中度或重度。住院患者的并发症发生率为37%，门诊患者为40%。不良反应大多表现为头痛，每组约三分之二的病例非常轻微，出现并发症的住院患者中有15%、门诊患者中有24%为中度或重度。与接受10毫升造影剂的门诊患者相比，接受8毫升造影剂的门诊患者中、重度反应的发生率较低。门诊进行碘帕醇腰椎脊髓造影是一种安全的检查方法。门诊方案大大降低了脊髓造影的成本，并间接增加了骨科和神经科病房的床位利用率。
