Furkalo N K, Lutaĭ M I, Zaĭtseva V I
Ter Arkh. 1985;57(9):34-7.
A total of 64 patients with coronary heart disease were examined using contrast coronaro-ventriculography, veloergometry and estimation of the lactic acid level in the coronary sinus blood. Fifty-seven patients were referred to obsidan therapy by the "blind" method. Two groups of patients with asynergies of ischemic and cicatricial genesis were singled out. The sensitivity of the ST segment depression and sigma R increment as objective signs of ischemia significantly reduced in the presence of postinfarction cardiosclerosis. Obsidan monotherapy caused a rise of load power and volume of work performed in the patients with asynergies of ischemic origin: an antianginal effect of the drug in such cases was comparable to that in the patients without disturbed myocardial regional cantractility.
对64例冠心病患者进行了对比冠状动脉心室造影、体力功率计检查以及冠状窦血乳酸水平评估。57例患者采用“盲法”接受黑曜石治疗。区分出两组缺血性和瘢痕性起源协同失调的患者。在心肌梗死后心脏硬化的情况下，ST段压低和R波增量作为缺血客观体征的敏感性显著降低。黑曜石单一疗法使缺血性起源协同失调患者的负荷功率和工作量增加：该药在这些病例中的抗心绞痛作用与心肌局部收缩性未受干扰的患者相当。
