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本文引用的文献

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Platelet count has a U-shaped association with mortality in hemodialysis patients.血小板计数与血液透析患者的死亡率呈 U 型关系。
Sci Rep. 2024 Nov 4;14(1):26572. doi: 10.1038/s41598-024-77718-7.
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Future Directions in Optimizing Anesthesia to Reduce Perioperative Acute Kidney Injury.优化麻醉以减少围手术期急性肾损伤的未来方向。
Am J Nephrol. 2023;54(9-10):434-450. doi: 10.1159/000533534. Epub 2023 Sep 22.
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Knowledge, attitude, and practice of patients receiving maintenance hemodialysis regarding hemodialysis and its complications: a single-center, cross-sectional study in Nanjing.接受维持性血液透析患者对血液透析及其并发症的知识、态度和实践:南京单中心横断面研究。
BMC Nephrol. 2023 Sep 20;24(1):275. doi: 10.1186/s12882-023-03320-0.
4
Risk prediction models for diabetic foot ulcer development or amputation: a review of reviews.糖尿病足溃疡或截肢风险预测模型:系统评价综述。
J Foot Ankle Res. 2023 Mar 16;16(1):13. doi: 10.1186/s13047-023-00610-6.
5
Impact of enhanced recovery after surgery program for hungry bone syndrome in patients on maintenance hemodialysis undergoing parathyroidectomy for secondary hyperparathyroidism.手术后加速康复计划对维持性血液透析患者饥饿骨综合征行甲状旁腺切除术治疗继发性甲状旁腺功能亢进的影响。
Ann Surg Treat Res. 2022 Nov;103(5):264-270. doi: 10.4174/astr.2022.103.5.264. Epub 2022 Nov 1.
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Propofol-Related Infusion Syndrome: A Clinical Review.丙泊酚输注综合征:临床综述
Cureus. 2022 Oct 17;14(10):e30383. doi: 10.7759/cureus.30383. eCollection 2022 Oct.
7
Physical function and all-cause mortality in patients with chronic kidney disease and end-stage renal disease: a systematic review and meta-analysis.慢性肾脏病和终末期肾病患者的身体功能与全因死亡率:系统评价和荟萃分析。
Int Urol Nephrol. 2023 May;55(5):1219-1228. doi: 10.1007/s11255-022-03397-w. Epub 2022 Nov 2.
8
Role of daytime variation in pharmaceutical effects of sufentanil, dezocine, and tramadol: A matched observational study.舒芬太尼、地佐辛和曲马多药物效应的日间变化作用:一项配对观察性研究。
Front Pharmacol. 2022 Sep 16;13:993506. doi: 10.3389/fphar.2022.993506. eCollection 2022.
9
Chronic kidney disease and anaesthesia.慢性肾脏病与麻醉
BJA Educ. 2022 Aug;22(8):321-328. doi: 10.1016/j.bjae.2022.03.005. Epub 2022 Jun 15.
10
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury.为急性肾损伤的危重患者提供最佳肾脏替代治疗。
Intensive Care Med. 2022 Oct;48(10):1368-1381. doi: 10.1007/s00134-022-06851-6. Epub 2022 Sep 6.

一名接受维持性血液透析的肾衰竭患者糖尿病足截肢的麻醉管理:病例报告与简短交流

Anesthetic management of diabetic foot amputation in a patient with renal failure and maintenance hemodialysis: case report and short communication.

作者信息

Wu Meng-Hao, Wei Ling, Li Pei, Zhang Chi, Wang Yan, Guo Quan-Zhou

机构信息

Department of Operation and Anaesthesia, Xingtai Central Hospital Xingtai 054000, Hebei, China.

出版信息

Am J Transl Res. 2025 Jul 15;17(7):5214-5220. doi: 10.62347/UMOA1809. eCollection 2025.

DOI:10.62347/UMOA1809
PMID:40821029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12351601/
Abstract

Chronic kidney disease (CKD) can progress to an advanced stage, eventually developing into end-stage renal disease (ESRD). Currently, the only effective treatment for ESRD is renal replacement therapy, with maintenance hemodialysis (MHD) being the most widely used modality, accounting for approximately 90% of all dialysis patients. However, the perioperative risk of surgery and anesthesia in these patients remains extremely high. Therefore, careful selection of surgical timing, appropriate anesthetic agents, and suitable anesthetic techniques is crucial. This report describes the anesthetic management of a 62-year-old female patient who had been hospitalized in the orthopedic ward for nine months due to left toe necrosis secondary to diabetic foot, in the setting of CKD requiring MHD. She was later admitted to Xingtai Central Hospital with progressive necrosis involving the left second and third toes and extending to the dorsum and plantar aspect of the foot. The patient was diagnosed with left-sided diabetic foot necrosis, stage 5 CKD, type 2 diabetes mellitus with multiple complications, grade 3 hypertension (high risk), and chronic hepatitis B infection. An elective transtibial (below-knee) amputation of the left lower limb was planned. Anesthesia was provided using color Doppler ultrasound-guided left iliac fascia block, left lateral femoral cutaneous nerve block, and left sciatic nerve block. Intravenous isoproterenol infusion, dexmedetomidine, and dizocine injection were administered for intraoperative sedation and analgesia. The patient's intraoperative vital signs remained stable. Postoperatively, the patient was awake, in good general condition, and was transferred to the ward with regular monitoring.

摘要

慢性肾脏病(CKD)可进展至晚期,最终发展为终末期肾病(ESRD)。目前,ESRD唯一有效的治疗方法是肾脏替代治疗,维持性血液透析(MHD)是应用最广泛的方式,约占所有透析患者的90%。然而,这些患者手术和麻醉的围手术期风险仍然极高。因此,仔细选择手术时机、合适的麻醉药物和恰当的麻醉技术至关重要。本报告描述了一名62岁女性患者的麻醉管理情况,该患者因糖尿病足继发左足趾坏死在骨科病房住院9个月,患有需要MHD的CKD。她后来因左第二和第三足趾渐进性坏死并蔓延至足背和足底而入住邢台市中心医院。该患者被诊断为左侧糖尿病足坏死、CKD 5期、2型糖尿病伴多种并发症、3级高血压(高危)和慢性乙型肝炎感染。计划对左下肢进行择期经胫骨(膝下)截肢术。采用彩色多普勒超声引导下左髂筋膜阻滞、左股外侧皮神经阻滞和左坐骨神经阻滞进行麻醉。术中静脉输注异丙肾上腺素、右美托咪定和地佐辛注射液用于镇静和镇痛。患者术中生命体征保持稳定。术后,患者清醒,一般情况良好,经定期监测后转入病房。