Suppr超能文献

空气污染对慢性气道狭窄的影响。

Impact of Air Pollution on Chronic Airway Narrowing.

作者信息

Vongelis Pavlos, Bakakos Petros, Rovina Nikoleta, Koulouris Nikolaos

机构信息

First Department of Respiratory Medicine, Medical School, Sotiria Hospital, National and Kapodistrian University of Athens, Athens, GRC.

出版信息

Cureus. 2025 Jul 17;17(7):e88135. doi: 10.7759/cureus.88135. eCollection 2025 Jul.

Abstract

INTRODUCTION

The increasing availability of data from electronic health records in healthcare organizations and systems has made it feasible to assess the relationship between various environmental parameters (e.g., pollution levels, meteorological data), hospital admissions, morbidity, and mortality associated with lung diseases. This study aimed to assess the correlation between air pollution levels and respiratory function parameters in patients with chronic obstructive lung diseases residing in various regions of the Attica Basin, Greece.

MATERIALS AND METHODS

Air pollution measurements were obtained from the Department of Atmospheric Quality of the Greek Ministry of Environment and Energy. In particular, data from daily bulletins and air pollution measurements were utilized. Numerical averages were calculated across all monitoring stations.

RESULTS

The analysis revealed statistically significant negative correlations between the concentrations of tropospheric ozone (O₃), sulfur dioxide (SO₂), nitrogen dioxide (NO₂), carbon monoxide (CO), and particulate matter (PM₁₀) and the respiratory parameters forced vital capacity (FVC%pred), forced expiratory volume in one second (FEV₁%pred), forced mid-expiratory flow between 25 and 75% of FVC (FEFpred), and peak expiratory flow (PEF%pred) on the day of examination (Day 0).

CONCLUSIONS

Air pollution measurements were found to be significantly and negatively correlated with lung function parameters. Specifically, increased concentrations of O, CO, SO, NO, and PM were significantly associated with lower values of the measured lung function parameters. Climate change may significantly affect future levels of O and the other air pollutants studied in this work. Many regions may face substantial increases in their concentrations, despite the implementation of emission reduction measures. This study clearly highlights the adverse effects of the examined air pollutants on key lung function parameters associated with obstructive lung diseases.

摘要

引言

医疗保健组织和系统中电子健康记录数据的日益可得,使得评估各种环境参数(如污染水平、气象数据)与医院入院率、发病率以及与肺部疾病相关的死亡率之间的关系成为可能。本研究旨在评估居住在希腊阿提卡盆地不同地区的慢性阻塞性肺疾病患者的空气污染水平与呼吸功能参数之间的相关性。

材料与方法

空气污染测量数据来自希腊环境与能源部大气质量司。具体而言,利用了每日公报中的数据和空气污染测量值。计算了所有监测站的数值平均值。

结果

分析显示,对流层臭氧(O₃)、二氧化硫(SO₂)、二氧化氮(NO₂)、一氧化碳(CO)和颗粒物(PM₁₀)的浓度与检查当天(第0天)的呼吸参数用力肺活量(FVC%pred)、一秒用力呼气量(FEV₁%pred)、FVC的25%至75%之间的用力呼气中期流速(FEFpred)和呼气峰值流速(PEF%pred)之间存在统计学上显著的负相关。

结论

发现空气污染测量值与肺功能参数显著负相关。具体而言,O、CO、SO、NO和PM浓度的增加与所测肺功能参数的较低值显著相关。气候变化可能会显著影响未来O以及本研究中所涉及的其他空气污染物的水平。尽管实施了减排措施,但许多地区这些污染物的浓度可能会大幅增加。本研究清楚地突出了所研究的空气污染物对与阻塞性肺疾病相关的关键肺功能参数的不利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/12357164/beaf937860bb/cureus-0017-00000088135-i01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验