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以中性粒细胞为主的腹膜结核合并输卵管炎酷似卵巢癌:一例报告

Neutrophil-Predominant Peritoneal Tuberculosis With Salpingitis Mimicking Ovarian Cancer: A Case Report.

作者信息

Almarzooqi Noura, Kafafi Radwa, Abbas Aymen, Alghefari Amal

机构信息

Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, ARE.

出版信息

Cureus. 2025 Jul 15;17(7):e88009. doi: 10.7759/cureus.88009. eCollection 2025 Jul.

Abstract

Tuberculosis (TB) is caused by . It is a multisystem infection, but the most common manifestation is pulmonary. TB is the leading cause of death among infectious diseases. Abdominal TB is a form of extrapulmonary TB (EPTB) that often presents nonspecifically and can result from genitourinary or hematogenous spread. We present the case of a 20-year-old Bangladeshi woman who presented with a two-month history of fever and night sweats accompanied by vomiting, tachycardia, and tachypnea. Laboratory investigations revealed elevated inflammatory markers, lactate dehydrogenase, and cancer antigen 125. QuantiFERON-TB (QIAGEN N.V., Venlo, Netherlands) was positive. An abdominal ultrasound showed free fluid throughout the abdomen. A CT scan of the abdomen revealed thickening and enhancement of the peritoneum, omental caking, and bilateral bulky ovaries measuring up to 8.5 x 5.4 cm on the right side, raising suspicion of malignancy. However, an MRI showed that the pelvic masses were, in fact, bilateral hydrosalpinx. Peritoneal analysis indicated a serum ascites albumin gradient (SAAG) of less than 1.1, suggesting peritonitis with neutrophil predominance. Acid-fast bacillus (AFB) culture of the peritoneal fluid grew . Abdominal TB and ovarian cancers can overlap in clinical presentation, especially in young female patients. Imaging may be misleading, as seen in this case. Imaging modalities may assist in the diagnosis; further exploration, particularly diagnostic laparoscopy with biopsy, is required for suspected ovarian cancer and EPTB.

摘要

结核病(TB)由……引起。它是一种多系统感染,但最常见的表现是肺部感染。结核病是传染病中主要的死亡原因。腹部结核是肺外结核(EPTB)的一种形式,通常表现不具特异性,可由泌尿生殖系统或血行播散引起。我们报告一例20岁孟加拉国女性病例,该患者有两个月发热、盗汗病史,伴有呕吐、心动过速和呼吸急促。实验室检查显示炎症标志物、乳酸脱氢酶和癌抗原125升高。结核菌素定量检测(QIAGEN N.V.,荷兰芬洛)呈阳性。腹部超声显示全腹有游离液体。腹部CT扫描显示腹膜增厚、强化,网膜饼状增厚,双侧卵巢肿大,右侧最大径达8.5×5.4cm,怀疑为恶性肿瘤。然而,磁共振成像显示盆腔肿块实际上是双侧输卵管积水。腹膜分析显示血清腹水白蛋白梯度(SAAG)小于1.1,提示以中性粒细胞为主的腹膜炎。腹膜液抗酸杆菌(AFB)培养长出……。腹部结核和卵巢癌在临床表现上可能重叠,尤其是在年轻女性患者中。如本病例所示,影像学检查可能会产生误导。影像学检查方式可能有助于诊断;对于疑似卵巢癌和EPTB,需要进一步检查,特别是诊断性腹腔镜检查及活检。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1317/12352705/cf286168d5dc/cureus-0017-00000088009-i01.jpg

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