Cardona Alejandro, Castro Sofia, Córdoba Naomi, Cardona Valeria
Pathology, Universidad Universidad Escuela de Ingeniería de Antioquia, Hospital Pablo Tobón Uribe, Medellín, COL.
School of Medicine, Universidad Universidad Escuela de Ingeniería de Antioquia, Hospital Pablo Tobón Uribe, Medellín, COL.
Cureus. 2025 Jul 15;17(7):e88041. doi: 10.7759/cureus.88041. eCollection 2025 Jul.
This case report presents an atypical manifestation of sarcoidosis with neurological onset, characterized by paroxysmal seizure episodes accompanied by transient loss of consciousness in the absence of other clinical symptoms. Although sarcoidosis usually presents with multisystem involvement, neurologic manifestations are rare. This case emphasizes the importance of including neurosarcoidosis in the differential diagnosis of unexplained neurological events, particularly when granulomatous disease is suspected, and underscores the need to thoroughly exclude infectious and neoplastic causes.
本病例报告展示了结节病以神经系统起病的非典型表现,其特征为阵发性癫痫发作并伴有短暂意识丧失,且无其他临床症状。尽管结节病通常表现为多系统受累,但神经系统表现较为罕见。该病例强调了在不明原因的神经系统事件鉴别诊断中纳入神经结节病的重要性,尤其是在怀疑存在肉芽肿性疾病时,并强调了彻底排除感染性和肿瘤性病因的必要性。