Liang Ching Hei, Wong K C, Lacambra Maribel D, Chu Winnie C W
Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.
Orthopaedic Oncology, Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.
Int Med Case Rep J. 2025 Aug 12;18:1021-1028. doi: 10.2147/IMCRJ.S529233. eCollection 2025.
Lymphangiomas, predominantly observed in pediatric populations, can occasionally be acquired in adulthood. They are rare benign tumors mostly found in the head and neck region, with solitary cystic lymphangioma in bone being very rare.
We report an uncommon case of a solitary cystic lymphangioma in the talus bone of a 19-year-old Chinese female presented with a history of enduring ankle swelling, rest pain, and frequent sprains. The patient's T2-weighted Magnetic Resonance Imaging (MRI) revealed a cystic bone lesion with multiple internal fluid levels, which initially suggested a Giant Cell Tumor (GCT) or chondroblastoma with secondary Aneurysmal Bone Cyst (ABC) change. However, histopathological examination of the tissue sample obtained through curettage suggested the diagnosis of intraosseous lymphangioma. The postoperative period was uneventful with no complications. Patients restored near normal ankle range of motion and there have been no signs of recurrence.
This case demonstrates the importance of considering a broad differential diagnosis when evaluating bone lesions, and it underlines the need to correlate pathological findings with radiographic images and clinical examination for an accurate diagnosis.
淋巴管瘤主要见于儿童群体,偶尔也可在成年期出现。它们是罕见的良性肿瘤,大多位于头颈部,骨内孤立性囊状淋巴管瘤极为罕见。
我们报告一例罕见病例,一名19岁中国女性距骨出现孤立性囊状淋巴管瘤,有长期踝关节肿胀、静息痛及频繁扭伤史。患者的T2加权磁共振成像(MRI)显示一个有多个内部液平的囊性骨病变,最初提示为巨细胞瘤(GCT)或成软骨细胞瘤伴继发性骨囊肿(ABC)改变。然而,通过刮除术获取的组织样本的组织病理学检查提示为骨内淋巴管瘤。术后恢复顺利,无并发症。患者踝关节活动范围恢复接近正常,且无复发迹象。
本病例表明在评估骨病变时考虑广泛鉴别诊断的重要性,并强调需要将病理结果与影像学图像及临床检查相结合以获得准确诊断。