孕激素序贯疗法对围绝经期功能失调性子宫出血患者卵泡刺激素（FSH）、黄体生成素（LH）及雌二醇（E2）的影响
Effect of progesterone sequential therapy on follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) in perimenopausal dysfunctional uterine bleeding.
作者信息
Wu Song, Wang Huiru, Zhao Yuwei, Tang Bo, Zhang Qi, Li Dapeng
机构信息
Yanshan University, Post Doctoral Station of Control Science and Engineering, Qinhuangdao Hospital of Traditional Chinese Medicine, Qinhuangdao, Hebei Province, China.
Hebei North University, Graduate School, Zhangjiakou, Hebei Province, China.
出版信息
J Med Biochem. 2025 Jun 13;44(3):653-659. doi: 10.5937/jomb0-53229.
BACKGROUND
Perimenopausal dysfunctional uterine bleeding (PDUB) is a common gynaecological disease with various clinical treatment options. The objective of this work was to investigate the clinical effect of female progesterone sequential therapy (FPST) on PDUB and follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2).
METHODS
140 cases of PDUB patients were enrolled and randomly rolled into an observation (Obs) group and a control (Ctrl) group, with 70 cases in each. The patients in the Ctrl group were given pure curettage treatment, and those in the Obs group were supplemented with FPST based on the intervention in the Ctrl group.
背景
围绝经期功能失调性子宫出血（PDUB）是一种常见的妇科疾病，有多种临床治疗选择。本研究的目的是探讨雌孕激素序贯疗法（FPST）对PDUB以及促卵泡生成素（FSH）、促黄体生成素（LH）和雌二醇（E2）的临床疗效。
方法
纳入140例PDUB患者，随机分为观察组（Obs）和对照组（Ctrl），每组70例。对照组患者接受单纯刮宫治疗，观察组患者在对照组干预的基础上补充FPST。
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