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现代植入式心脏复律除颤器和心脏再同步治疗除颤器的电池寿命

Battery Longevity in Modern Implantable Cardioverter-Defibrillators and Cardiac Resynchronization Therapy-Defibrillators.

作者信息

Nishino Kotaro, Temma Taro, Watanabe Masaya, Nakao Motoki, Kawasaki Masahiro, Shimano Kintaro, Kawakami Kei, Saito Shota, Koya Jiro, Tatsuta Daishiro, Natsui Hiroyuki, Koizumi Takuya, Kadosaka Takahide, Koya Taro, Kamiya Kiwamu, Nagai Toshiyuki, Anzai Toshihisa

机构信息

Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Hokkaido University Sapporo Japan.

Department of Cardiovascular Medicine Hokko Memorial Hospital Sapporo Japan.

出版信息

J Arrhythm. 2025 Aug 15;41(4):e70175. doi: 10.1002/joa3.70175. eCollection 2025 Aug.

Abstract

BACKGROUND

Battery longevity in high-voltage devices (HVDs), specifically implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy-defibrillators (CRT-Ds), is critical for reducing the frequency of generator replacements, minimizing procedural risks, and enhancing patient outcomes. Despite technological advancements, significant variability in battery performance remains among the major manufacturers. This study aimed to evaluate the battery longevity among ICDs and CRT-Ds from the major manufacturers implanted at a single institution and identify the factors influencing battery depletion.

METHODS

We conducted a retrospective analysis of 353 patients implanted with HVDs (63 Abbott, 150 Boston Scientific, 140 Medtronic) at Hokkaido University Hospital between 2012 and 2021. Kaplan-Meier curves and Cox proportional hazards models were used to analyze the device longevity, with a primary endpoint of the time to battery depletion, defined by the elective replacement indicator. A multivariate analysis adjusted for the potential confounders.

RESULTS

Boston Scientific devices exhibited a significantly longer battery life than Abbott and Medtronic devices ( < 0.001), with a 6-year replacement-free survival of 99% for ICDs and 93% for CRT-Ds. A multivariate analysis identified the device manufacturer, device type (ICD vs. CRT-D), and ventricular pacing rate as independent predictors of battery depletion ( < 0.001).

CONCLUSION

Battery longevity differed significantly by the manufacturer, which may influence device selection. Devices with a longer battery life may help reduce the replacement frequency and could potentially contribute to improved patient outcomes and cost-effectiveness.

摘要

背景

高压设备(HVDs),特别是植入式心脏复律除颤器(ICDs)和心脏再同步治疗除颤器(CRT-Ds)的电池寿命,对于减少发生器更换频率、将手术风险降至最低以及改善患者预后至关重要。尽管技术有所进步,但主要制造商之间的电池性能仍存在显著差异。本研究旨在评估在单一机构植入的主要制造商生产的ICDs和CRT-Ds的电池寿命,并确定影响电池耗尽的因素。

方法

我们对2012年至2021年期间在北海道大学医院植入HVDs的353例患者(63例雅培、150例波士顿科学、140例美敦力)进行了回顾性分析。采用Kaplan-Meier曲线和Cox比例风险模型分析设备寿命,主要终点为电池耗尽时间,由择期更换指标定义。进行多变量分析以调整潜在的混杂因素。

结果

波士顿科学的设备显示出比雅培和美敦力的设备显著更长的电池寿命(<0.001),ICDs的6年无更换生存率为99%,CRT-Ds为93%。多变量分析确定设备制造商、设备类型(ICD与CRT-D)和心室起搏率为电池耗尽的独立预测因素(<0.001)。

结论

不同制造商的电池寿命存在显著差异,这可能会影响设备的选择。电池寿命更长的设备可能有助于降低更换频率,并可能有助于改善患者预后和成本效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bab4/12355725/6b3c438e988c/JOA3-41-e70175-g002.jpg

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