Redefining "normal": discovery of aneuploid epithelial cells in healthy breast tissue.
作者信息
Chen Xiaoyan, Liu Xiaoling, Xue Jiapeng, Li Zhi
机构信息
Department of Rehabilitation, Taihe Hospital, Hubei University of Medicine, Shiyan, China.
Medical College of Nanchang Institute of Technology, Nanchang, Jiangxi, China.
出版信息
Front Oncol. 2025 Jul 31;15:1558977. doi: 10.3389/fonc.2025.1558977. eCollection 2025.
Abstract
摘要
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Nat Genet. 2024 Dec;56(12):2753-2762. doi: 10.1038/s41588-024-01988-0. Epub 2024 Nov 20.
2
Normal breast tissues harbour rare populations of aneuploid epithelial cells.正常乳腺组织中存在少量非整倍体上皮细胞群体。
Nature. 2024 Dec;636(8043):663-670. doi: 10.1038/s41586-024-08129-x. Epub 2024 Nov 20.
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Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns.染色体进化筛选重现了组织特异性肿瘤非整倍体模式。
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