Mokri Hamraz, van Baal Pieter, Mölken Maureen Rutten-van
Erasmus School of Health Policy and Management (ESHPM), Erasmus University Rotterdam, Rotterdam, The Netherlands.
Institute for Medical Technology Assessment (iMTA), Erasmus University Rotterdam, Rotterdam, The Netherlands.
Pharmacoeconomics. 2025 Aug 18. doi: 10.1007/s40273-025-01533-9.
Heart failure (HF) is a complex clinical syndrome associated with high mortality and extensive healthcare use. Using longitudinal data, we aimed to estimate the lifetime healthcare and long-term care (LTC) use and costs of Dutch patients with HF.
We used linked administrative data on mortality, LTC, and healthcare use covering the entire Dutch population for the period 2013-2024. Newly diagnosed patients with HF were defined as patients who were not hospitalized for HF 2 years before their index hospitalization for HF in 2015. Using regression modeling, we estimated hospitalized patients' life expectancy and lifetime healthcare costs as a function of age, sex, comorbidity, and income (all costs were adjusted to 2021 values).
We identified 21,011 unique hospitalized patients with HF (mean age 80 years), of whom 86% died during follow-up. Estimated lifetime total healthcare and LTC costs varied between €35,000 and €170,000, depending on patient characteristics. Lifetime LTC costs varied between €9000 and €50,000. While comorbidity affects life expectancy substantially, it did not have a strong impact on lifetime costs. Income level affects costs more than comorbidities, and lower-income groups incur higher lifetime LTC costs.
Despite people with lower incomes having shorter lifespans than those with higher incomes, their lifetime LTC costs are higher. However, people with higher incomes have higher hospital costs, partly owing to their longer life expectancy.
心力衰竭(HF)是一种复杂的临床综合征,死亡率高且医疗保健使用广泛。利用纵向数据,我们旨在估计荷兰心力衰竭患者的终身医疗保健和长期护理(LTC)使用情况及成本。
我们使用了2013 - 2024年期间涵盖荷兰全体人口的关于死亡率、长期护理和医疗保健使用的关联行政数据。新诊断的心力衰竭患者定义为在2015年首次因心力衰竭住院前2年未因心力衰竭住院的患者。使用回归模型,我们估计了住院患者的预期寿命和终身医疗保健成本,作为年龄、性别、合并症和收入的函数(所有成本均调整为2021年的值)。
我们识别出21,011名独特的因心力衰竭住院的患者(平均年龄80岁),其中86%在随访期间死亡。根据患者特征,估计的终身总医疗保健和长期护理成本在35,000欧元至170,000欧元之间。终身长期护理成本在9000欧元至50,000欧元之间。虽然合并症对预期寿命有重大影响,但对终身成本影响不大。收入水平对成本的影响大于合并症,低收入群体的终身长期护理成本更高。
尽管低收入人群的寿命比高收入人群短,但他们的终身长期护理成本更高。然而,高收入人群的住院成本更高,部分原因是他们的预期寿命更长。