Rauber A, Heard J
Vet Hum Toxicol. 1985 Dec;27(6):498-502.
Commonly used references present a very gloomy prognosis for castor seed ingestion. This appears to be based chiefly on extrapolations from laboratory animal studies of toxicity of the component, ricin. This is not in concordance with actual experience when actual case report experience is sought out and examined in detail. The literature has been confused by recursive references among secondary sources and mortality statistics have been distorted by reliance on data generated nearly a century ago which do not accurately reflect the capabilities of modern medical management. This is elucidated by actually tracking down and studying difficult-to-find original case reports from the early decades of the 20th century. It is time to reappraise our estimates of the hazard of ingesting castor seeds in the light of present day medical capabilities.
常用参考文献对蓖麻子摄入的预后描述非常悲观。这似乎主要基于对蓖麻毒素这种成分毒性的实验动物研究推断而来。当详细查找并审视实际病例报告经验时，这与实际情况并不相符。二手资料之间的反复引用使文献变得混乱，而死亡率统计因依赖近一个世纪前的数据而被扭曲，这些数据无法准确反映现代医疗管理的能力。通过实际追踪和研究20世纪早期几十年间难以找到的原始病例报告可以阐明这一点。鉴于当今的医疗能力，是时候重新评估我们对摄入蓖麻子危害的估计了。
