Minocha A, Barth J T, Roberson D G, Herold D A, Spyker D A
Vet Hum Toxicol. 1985 Dec;27(6):533-6.
Ethanol is known to impair cognitive and psychomotor function in high doses. We studied the impairment of cognitive, psychomotor and behavioral responses in controlled environment in a group of healthy young social drinkers at below and above legal limit for presumption of intoxication (100 mg/dl). Attention, concentration, auditory-verbal memory and memory for visuospatial information were significantly impaired at both levels. Motor speed was impaired only at higher levels though fine coordination was impaired at both doses. Females showed more impairment on visual as well as auditory-verbal memory functions. With low doses, choice reaction time improved with the nonpreferred hand.
已知高剂量乙醇会损害认知和精神运动功能。我们在可控环境中，对一组健康的年轻社交饮酒者进行了研究，这些饮酒者的血液酒精浓度分别处于推定醉酒的法定限度（100毫克/分升）以下和以上。在这两个浓度水平下，注意力、专注力、听觉语言记忆和视觉空间信息记忆均受到显著损害。虽然精细协调能力在两个剂量水平下均受损，但运动速度仅在较高浓度水平下受到损害。女性在视觉以及听觉语言记忆功能方面表现出更多损害。在低剂量时，非优势手的选择反应时间有所改善。
