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[不同蛋白质含量饮食大鼠小肠黏膜的结构特征]

[Structural characteristics of the small intestine mucosa of rats on diets with varying amounts of protein].

作者信息

Gadzhieva Z M

出版信息

Vopr Pitan. 1985 Sep-Oct(5):29-32.

PMID:4082516
Abstract

The small bowel mucosa of rats fed diets containing 4 and 35% of protein in terms of caloricity over 1 month demonstrated, as compared with control (18% of protein), alterations in the nuclei, in the degree of lymphoid infiltration, number of mitoses and gobiet cells in the epithelium, pointing to changes or impairment of maturation and differentiation of the cells of the epithelial layer. The degree of mucosa plasmatization was also discovered to be reduced as compared with control. The rearrangements in question attest to a decrease in the resistance of the mucosa. These rearrangements are more demonstrable in the intestine of rats which received low-protein diets, being far more pronounced in the distal parts.

摘要

给大鼠喂食热量中蛋白质含量分别为4%和35%的日粮1个月后,其小肠黏膜与对照组(蛋白质含量18%)相比,细胞核、淋巴样浸润程度、上皮细胞有丝分裂数量及杯状细胞均发生了变化,表明上皮层细胞成熟和分化出现改变或受损。与对照组相比,还发现黏膜浆细胞化程度降低。上述改变证明黏膜抵抗力下降。这些改变在低蛋白日粮喂养的大鼠肠道中更明显,在远端部分更为显著。

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