Xia Yang, Thiruvengadam Shreyas, Khoo Boyuan, Lam Mark, Hockley Joe, Jansen Shirley
Department of Neurosurgery, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Department of Vascular and Endovascular Surgery, Sir Charles Gairdner Hospital, Nedlands, Perth, Western Australia, Australia.
J Neurosurg Case Lessons. 2025 Aug 18;10(7). doi: 10.3171/CASE25151.
Malignant peripheral nerve sheath tumors are a rare, aggressive form of soft tissue sarcoma with a dismal prognosis. Little progression has been made in understanding their pathogenesis, natural history, clinical management, and outcomes over the last few decades. The cornerstone of treatment is cytoreduction in the form of surgery. However, when in the lumbar region, the inferior vena cava poses a limitation for executing anterior approaches. Although performed in other operations, elective caval division for access purposes has not been described as an approach to anterior column resection in spinal operations.
The authors present the first documented case of planned division and mobilization of the vena cava supported by venous-venous bypass in order to achieve gross-total resection of a lower lumbar malignant peripheral nerve sheathe tumor as part of a two-stage procedure.
Inferior vena cava division and reanastomosis is a novel technique that can be used to widen surgical corridors in anterior approaches to the lumbar spine, and one that proves useful in en bloc resections. Venous-venous bypass can minimize impact on right heart filling during prolonged surgery. https://thejns.org/doi/10.3171/CASE25151.
恶性外周神经鞘瘤是一种罕见的、侵袭性软组织肉瘤,预后较差。在过去几十年里,对其发病机制、自然病程、临床管理及治疗结果的了解进展甚微。治疗的基石是以手术形式进行肿瘤细胞减灭。然而,当肿瘤位于腰椎区域时,下腔静脉会限制前路手术的实施。尽管在其他手术中会进行选择性腔静脉离断以获得手术入路,但在脊柱手术中,尚未有将其作为前路椎体切除入路的描述。
作者报道了首例有记录的病例,在静脉-静脉转流辅助下计划性离断并游离腔静脉,作为两阶段手术的一部分,以实现下腰椎恶性外周神经鞘瘤的全切除。
下腔静脉离断与再吻合是一种可用于扩大腰椎前路手术通道的新技术,在整块切除术中被证明是有用的。静脉-静脉转流可在长时间手术中减少对右心充盈的影响。https://thejns.org/doi/10.3171/CASE25151 。