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良性外阴平滑肌瘤:1例罕见病例报告

Benign Vulval Leiomyoma: Report of a Rare Case.

作者信息

Hassan D, Percholli Ramasubramanian S

机构信息

Obstetrics and Gynaecology, Wythenshawe Hospital, Manchester, GBR.

出版信息

Cureus. 2025 Aug 17;17(8):e90283. doi: 10.7759/cureus.90283. eCollection 2025 Aug.

Abstract

A vulval leiomyoma is an uncommon, benign mass often misdiagnosed as a Bartholin cyst. Its precise etiology is currently unknown, though it typically arises from the deep connective tissue within the labia majora. Clinically, it presents as a slowly developing perineal mass, with pain and distress being the primary symptoms. We present the case of a 41-year-old woman with a one-year history of a gradually expanding vaginal mass. Examination revealed a left-sided vulval mass over 6 cm. Surgical excision was performed, and intraoperatively, an additional 7 cm mass extending deep into the perineum was found on the right vulva, confirming leiomyoma rather than a Bartholin's cyst. Histopathological examination confirmed a smooth muscle tumor with myxoid stroma, no atypia or necrosis, and postoperative MRI showed multifocal confluent soft tissue nodules in the perineum. Differentiation from a Bartholin cyst can be challenging due to similar presenting symptoms, including erythema, irritation, localized enlargement, and an asymptomatic mass. However, specific physical findings, such as inverted labia minora and a firm consistency of the swelling, can support a diagnosis of vulvar leiomyoma, contrasting with the everted labia minora and cystic structure seen in Bartholin cysts. Histopathological examination and MRI findings are crucial for accurate diagnosis and for distinguishing between benign and malignant forms. Surgical excision is the definitive treatment for benign vulval leiomyomas.

摘要

外阴平滑肌瘤是一种罕见的良性肿块,常被误诊为巴氏腺囊肿。其确切病因目前尚不清楚,不过它通常起源于大阴唇内的深部结缔组织。临床上,它表现为一个缓慢生长的会阴肿块,疼痛和不适是主要症状。我们报告一例41岁女性,有一个逐渐增大的阴道肿块,病史一年。检查发现左侧外阴有一个超过6厘米的肿块。进行了手术切除,术中在右侧外阴发现一个额外的7厘米肿块,深入会阴,确诊为平滑肌瘤而非巴氏腺囊肿。组织病理学检查证实为具有黏液样基质的平滑肌瘤,无异型性或坏死,术后MRI显示会阴有多灶性融合性软组织结节。由于表现症状相似,包括红斑、刺激、局部肿大和无症状肿块,与巴氏腺囊肿进行鉴别可能具有挑战性。然而,一些特定的体格检查发现,如小阴唇内翻和肿胀质地坚硬,可支持外阴平滑肌瘤的诊断,这与巴氏腺囊肿中所见的小阴唇外翻和囊性结构形成对比。组织病理学检查和MRI结果对于准确诊断以及区分良性和恶性形式至关重要。手术切除是良性外阴平滑肌瘤的确定性治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b3/12358078/48a4c76e51ab/cureus-0017-00000090283-i01.jpg

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