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Neoadjuvant Intra-arterial Cytoreductive Chemotherapy Improves Outcomes in Lacrimal Gland Adenoid Cystic Carcinoma.新辅助动脉内细胞减灭化疗改善泪腺腺样囊性癌的预后。
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泪腺腺样囊性癌的治疗进展

Advances in treatment of adenoid cystic carcinoma of the lacrimal gland.

作者信息

Li Jin-Bei, Ma Jian-Min

机构信息

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

出版信息

Int J Ophthalmol. 2025 Aug 18;18(8):1570-1578. doi: 10.18240/ijo.2025.08.20. eCollection 2025.

DOI:10.18240/ijo.2025.08.20
PMID:40827280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12311449/
Abstract

Adenoid cystic carcinoma of the lacrimal gland (LGACC) is the most common type of malignant epithelial tumor of the lacrimal gland, which is characterized by a high recurrence rate, perineural invasion, and a propensity to metastasize to distant sites. Due to its unclear pathogenesis, LGACC has a poor prognosis and a high mortality rate. In recent years, a range of radiotherapy and chemotherapy have been clinically applied, leading to a shift in the treatment approach for LGACC. This article discussed the advances being made in the treatment of LGACC and provides readers with an overview of the impact of LGACC treatment modalities on patient survival and prognostic levels.

摘要

泪腺腺样囊性癌（LGACC）是泪腺最常见的恶性上皮性肿瘤，其特点是复发率高、神经周围浸润以及易于远处转移。由于其发病机制尚不清楚，LGACC预后较差，死亡率高。近年来，一系列放疗和化疗已在临床上应用，导致LGACC的治疗方法发生了转变。本文讨论了LGACC治疗方面取得的进展，并为读者概述了LGACC治疗方式对患者生存率和预后水平的影响。