在人类前列腺癌中观察到环状片层。
Annulate lamellae observed in human prostatic carcinoma.
作者信息
Ohtsuki Y, Takeda I, Sonobe H, Akagi T, Dmochowski L
出版信息
Acta Pathol Jpn. 1985 Sep;35(5):1215-20. doi: 10.1111/j.1440-1827.1985.tb01011.x.
Annulate lamellae (AL) were observed in only three out of 40 cases of human prostatic carcinoma, but not in 20 cases of benign prostatic hyperplasia and 11 cases of presumably normal prostatic tissues. AL showed the continuity with the rough endoplasmic reticulum and seemingly the nuclear membrane consisting of lamellar or concentric arrangement of stacked membranes and occasionally annular structures. In addition, annuli were detected in the rough endoplasmic reticulum near the stacked membranes which were devoid of ribosomal attachment. These results disclosed that in human prostatic tissues, AL could be only rarely detected in actively dividing cancer cells, and were seemingly the temporary transitional structures transforming from the nuclear membrane to the rough endoplasmic reticulum.
在40例人类前列腺癌病例中，仅在3例中观察到环状片层（AL），而在20例良性前列腺增生和11例推测为正常的前列腺组织中未观察到。AL与粗面内质网连续，似乎与由堆叠膜的层状或同心排列以及偶尔的环状结构组成的核膜相连。此外，在没有核糖体附着的堆叠膜附近的粗面内质网中检测到环。这些结果表明，在人类前列腺组织中，AL仅在活跃分裂的癌细胞中很少被检测到，并且似乎是从核膜转变为粗面内质网的临时过渡结构。
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