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肢体缩短/再延长技术与组织再生技术在复杂下肢骨折合并软组织缺损保肢中的应用

[Application of limb shortening/re-lengthening technique and tissue regeneration technique in limb salvage for complex lower limb fractures combined with soft tissue defects].

作者信息

Liu Hong, Ren Yuanmeng, Yan Xianyan, Wang Baona, Wang Dong, Qiao Huyun, Guo Jinli, Zhang Yonghong

机构信息

Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan Shanxi, 030001, P. R. China.

Department of Academy of Medical Sciences, Shanxi Medical University, Taiyuan Shanxi, 030001, P. R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 Aug 15;39(8):1014-1019. doi: 10.7507/1002-1892.202504119.

Abstract

OBJECTIVE

To explore the effectiveness of limb shortening/re-lengthening technique combined with tissue regeneration technique in limb salvage for patients with complex lower limb fractures and soft tissue defects.

METHODS

Between January 2021 and December 2024, 12 patients with complex lower limb fractures and soft tissue defects caused by trauma were admitted. There were 10 males and 2 females; the age ranged from 18 to 46 years, with an average of 36 years. Among them, 1 case of open comminuted tibiofibular fracture caused bone necrosis and soft tissue infection; 4 cases of open tibiofibular fractures developed bone and soft tissue infections after being fixed with a combined external fixator, resulting in defects; 7 cases of closed tibial fractures that underwent internal fixation developed soft tissue infections, leading to bone and soft tissue necrosis. The time from injury to the formation of bone and soft tissue defects was 2-9 weeks, with an average of 6 weeks. The length of bone defects was 5.0-10.2 cm, with an average of 6.8 cm; the area of soft tissue defects was 32-54 cm , with an average of 43.9 cm . After admission, all patients underwent thorough debridement. The limb shortening treatment was performed after the wound had filled with fresh granulation tissue, and an Ilizarov ring-shaped external fixator was placed or replaced. The limb was shortened at a rate of 1 mm/day to reduce bone defects. At the same time, the soft tissue defects were repaired using the tissue regeneration technique. After the wound healed, osteotomy was performed, and limb lengthening was carried out at a rate of 1 mm/day. The lower limb full-length X-ray films were taken, and the lengthening was stopped when the lower limb alignment was restored. The healing condition of the wound was observed and the healing time was recorded.

RESULTS

One patient died due to a traffic accident during limb lengthening. The remaining 11 patients completed limb shortening and re-lengthening treatment and were followed up 18-36 months, with an average of 20 months. All 11 patients successfully preserved their limbs. The wound healing time was 4-12 weeks, with an average of 8 weeks; the limb shortening time was 4-8 weeks, with an average of 6 weeks; and the limb lengthening time was 4-12 weeks, with an average of 8 weeks. One patient experienced delayed bone mineralization during bone lengthening, and one had pin tract infection. Both were treated symptomatically. The lower limb mechanical axis of all 11 patients was restored, and they were able to walk independently.

CONCLUSION

The application of limb shortening/re-lengthening technique combined with tissue regeneration technique in the treatment of large bone and soft tissue defects not only effectively avoids the occurrence of nonunion at the apposition ends and increases the stability of the lower limb, but also significantly shortens the wound healing time, avoids the risk of soft tissue infection and increases the limb salvage rate. It can be used as a treatment technique for patients with complex lower limb fractures combined with soft tissue defects.

摘要

目的

探讨肢体缩短/再延长技术联合组织再生技术在复杂下肢骨折合并软组织缺损患者保肢治疗中的有效性。

方法

2021年1月至2024年12月,收治12例因创伤导致复杂下肢骨折合并软组织缺损的患者。其中男性10例,女性2例;年龄18~46岁,平均36岁。其中1例开放性胫腓骨粉碎性骨折导致骨坏死及软组织感染;4例开放性胫腓骨骨折采用组合式外固定架固定后发生骨与软组织感染,形成缺损;7例闭合性胫骨骨折行内固定术后发生软组织感染,导致骨与软组织坏死。从受伤至骨与软组织缺损形成的时间为2~9周,平均6周。骨缺损长度为5.0~10.2cm,平均6.8cm;软组织缺损面积为32~54cm²,平均43.9cm²。入院后,所有患者均接受了彻底清创。待创面长满新鲜肉芽组织后进行肢体缩短治疗,放置或更换Ilizarov环形外固定架。以每天1mm的速度缩短肢体以减少骨缺损。同时,采用组织再生技术修复软组织缺损。伤口愈合后,行截骨术,并以每天1mm的速度进行肢体延长。拍摄下肢全长X线片,当下肢力线恢复时停止延长。观察伤口愈合情况并记录愈合时间。

结果

1例患者在肢体延长过程中因交通事故死亡。其余11例患者完成了肢体缩短和再延长治疗,并进行了18~36个月的随访,平均20个月。11例患者均成功保肢。伤口愈合时间为4~12周,平均8周;肢体缩短时间为4~8周,平均6周;肢体延长时间为4~12周,平均8周。有1例患者在骨延长过程中出现骨矿化延迟,1例出现针道感染。均进行了对症治疗。11例患者下肢力学轴线均恢复,均能独立行走。

结论

肢体缩短/再延长技术联合组织再生技术应用于治疗大面积骨与软组织缺损,不仅有效避免了对接端骨不连的发生,增加了下肢稳定性,还显著缩短了伤口愈合时间,避免了软组织感染风险,提高了保肢率。可作为复杂下肢骨折合并软组织缺损患者的治疗技术。

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