Lo Piccolo Roberto, Cantagalli Michele Maria, Ferroni Tommaso, Fracchiolla Florinda, Morabito Antonino
Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy.
Department of Pediatric Surgery, Meyer Children's Hospital, Florence, Italy.
Front Pediatr. 2025 Aug 4;13:1579645. doi: 10.3389/fped.2025.1579645. eCollection 2025.
Appendicitis is the most frequent non-traumatic surgical emergency in children. While laparoscopic surgery is standard, postoperative recovery often involves pain, delayed bowel function, and reduced mobility. Osteopathic manipulative treatment (OMT) may improve recovery by addressing fascial restrictions and visceral dysfunction. This pilot study investigates OMT's effect on postoperative pain and hospital length of stay in pediatric patients undergoing appendectomy.
This non-randomized, time-controlled clinical trial was conducted at Meyer Pediatric Hospital (Florence, Italy) with 43 patients aged 5-17 undergoing laparoscopic appendectomy. Participants were divided by appendicitis type (complicated/uncomplicated) and treatment group (OMT vs. control). The OMT group received two standardized sessions within 48 h post-surgery. Primary outcomes included postoperative pain (assessed via Numeric Rating Scale) and hospital stay. Secondary outcomes included bowel function, mobilization, and nausea/vomiting. Data were analyzed using multivariate statistics and -tests, with < 0.05 as the significance threshold.
The OMT group showed a shorter mean hospital stay (4.6 vs. 7 days) and significantly greater reductions in abdominal and shoulder pain compared to controls. In uncomplicated appendicitis, pain reduction reached 3/10 vs. 1.7/10 in controls; in complicated cases, 3.6/10 vs. 1.8/10. Shoulder pain relief was also more pronounced in the OMT groups. Improvements in bowel function, mobilization, and nausea were observed in both groups, with no statistically significant differences.
This pilot study provides preliminary evidence that OMT may enhance postoperative recovery in pediatric appendectomy by reducing pain and potentially shortening hospital stays. Although not statistically significant due to the small sample size, the clinical relevance of these findings supports further investigation through larger, randomized trials.
阑尾炎是儿童最常见的非创伤性外科急症。虽然腹腔镜手术是标准术式,但术后恢复常伴有疼痛、肠功能延迟恢复以及活动能力下降。整骨手法治疗(OMT)可能通过解决筋膜限制和内脏功能障碍来促进恢复。这项前瞻性研究调查了OMT对接受阑尾切除术的儿科患者术后疼痛和住院时间的影响。
这项非随机、时间对照的临床试验在意大利佛罗伦萨的迈耶儿童医院进行,纳入43例年龄在5至17岁接受腹腔镜阑尾切除术的患者。参与者按阑尾炎类型(复杂/非复杂)和治疗组(OMT组与对照组)进行分组。OMT组在术后48小时内接受两次标准化治疗。主要结局指标包括术后疼痛(通过数字评分量表评估)和住院时间。次要结局指标包括肠功能、活动能力以及恶心/呕吐。数据采用多变量统计和t检验进行分析,以P < 0.05作为显著性阈值。
与对照组相比,OMT组的平均住院时间更短(4.6天对7天),腹部和肩部疼痛的减轻也更为显著。在非复杂性阑尾炎中,疼痛减轻程度为3/10,而对照组为1.7/10;在复杂性阑尾炎中,分别为3.6/10和1.8/10。OMT组肩部疼痛的缓解也更为明显。两组在肠功能、活动能力和恶心症状方面均有改善,但无统计学显著差异。
这项前瞻性研究提供了初步证据,表明OMT可能通过减轻疼痛并可能缩短住院时间来促进儿科阑尾切除术后的恢复。尽管由于样本量小,差异无统计学显著性,但这些发现的临床意义支持通过更大规模的随机试验进行进一步研究。